Objective
Background:
Traditionally, immunoassays have been separation based, meaning that the analyte of interest goes through several steps of antibody binding, washing and separation before final detection. This type of assay requires high use of consumables, which is expensive, and is time consuming due to all the steps. While, in a non-separation assay no separation steps are involved and the use of consumables is limited, making the assay less expensive and with a much shorter assay time.
A non-separation assay will typically be run on a clinical chemistry platform intended for high-throughput of analytes, making homogeneous non-separation immunoassays a high potential market growth opportunity.
Rationale:
There is a need for high sensitivity non-separation immunoassay technology for general clinical chemistry instrument platforms, in particular for large protein disease markers of low concentration such as NT-proBNP and PSA, and a long list of other plasma proteins, protein hormones and specific antibodies. Such new technology will significantly change the diagnostic industry and health care providers towards greater efficacy.
The goal of this project is to move immunoassays from slow and expensive methods to fast, high-throughput super-sensitive nanoparticle based methods, demonstrate it's working within the specifications, and generate intellectual property for such technology.
Methods:
To achieve the goal of this project, methods and techniques will be taken into use to optimise each component in the assay.
Perspectives:
When such technology was developed for small molecule markers 15 years ago, a big change in the diagnostic industry was seen, and two small SMEs grew into big industrial corporations. We foresee that similar effects will be seen when such technology is developed for large molecule markers.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- engineering and technology nanotechnology nano-materials
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-LIFESCIHEALTH-7
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
MOSS
Norway
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.