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Content archived on 2024-05-29

Novel post-genomic cell-based screens for drug targeting in membrane protein disorders

Objective

Elucidation of protein function is the next post-genomic challenge towards the understanding of biological processes in health and disease. Transcriptomics and proteomics approaches usually deliver long lists of "candidate" gene that are putatively associated with the respective disease. However, no functional information nor direct relationship with the pathology, is established. Strategies and tools are thus critically needed to distinguish genes and proteins with mere pathologic association from those primarily responsible for the basic cellular defect(s) in such pathologies. Membrane proteins, including receptors, channels, antibodies, transporters, etc. play major roles in cells and organisms as they are involved in important cellular mechanisms, such as communication, immunity, signalling and response to environmental stimuli.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2005-LIFESCIHEALTH-7
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

STREP - Specific Targeted Research Project

Coordinator

FUNDAC?O DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA
EU contribution
No data
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (7)

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