Objective The objective of the proposal is to establish stable cell lines that reliably reflect human cardiomyocyte properties by the development of models derived from human embryonic stem cells.The aim is to deliver reliable in vitro models that could be used by the pharmaceutical industry to replace experimental animals in:- investigations on pharmacological toxicity and safety of compounds in the drug discovery and development processes, and- the testing of toxic effects of chemicals according to the new system of the Community on the Registration, Evaluation and Authorisation of Chemicals (REACH).In the pharmaceutical industry reliable in vitro cell models would contribute to replace current techniques with animal experimentation in the selection and optimisation of lead compounds and in documentation of a selected drug candidate before it enters clinical phases. In the toxicity testing of chemical substances replacement of animal testing methods can be attained as well. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverymedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsmedical and health sciencesmedical biotechnologycells technologiesstem cells Programme(s) FP6-LIFESCIHEALTH - Life sciences, genomics and biotechnology for health: Thematic Priority 1 under the Focusing and Integrating Community Research programme 2002-2006. Topic(s) LSH-2005-1.2.3-4 - Development of new in vitro tests to replace animal experimentation LIFESCIHEALTH - Life sciences, genomics and biotechnology for health Call for proposal FP6-2005-LIFESCIHEALTH-7 See other projects for this call Funding Scheme STREP - Specific Targeted Research Project Coordinator LINKÖPING UNIVERSITY Address Linköping Sweden See on map Links Website Opens in new window EU contribution € 0,00 Participants (8) Sort alphabetically Sort by EU Contribution Expand all Collapse all CELLARTIS AB Sweden EU contribution € 0,00 Address Arvid wallgrens backe 20 Göteborg See on map Links Website Opens in new window EUROPEAN COMMISSION, DG JRC (JOINT RESEARCH CENTRE) Belgium EU contribution € 0,00 Address Rue de la loi 200 Brussels See on map Links Website Opens in new window GÖTEBORGS UNIVERSITET Sweden EU contribution € 0,00 Address Vasaparken Göteborg See on map Links Website Opens in new window H. LUNDBECK A/S Denmark EU contribution € 0,00 Address Ottiliavej 9 Valby See on map Links Website Opens in new window MULTI CHANNEL SYSTEMS MCS GMBH Germany EU contribution € 0,00 Address Aspenhaustrasse 21 Reutlingen See on map Links Website Opens in new window PHARMACELSUS GMBH Germany EU contribution € 0,00 Address Science park 2 Saarbrücken See on map Links Website Opens in new window PRESENS PRECISION SENSING GMBH Germany EU contribution € 0,00 Address Josef engert strasse 11 Regensburg See on map Links Website Opens in new window UNIVERSITÄT DES SAARLANDES Germany EU contribution € 0,00 Address Saarbrücken See on map Links Website Opens in new window
