Objective
Behavioural change is the most sensitive biological end-point signalling any alteration in the organism of a mouse. However, large-scale bio-assays of behaviour face limitations: outdated technology, need for space and specialized manpower, lack of standardisation, and increasing legal demands on animal husbandry. This has limited the use of behavioural methods to specialised laboratories, limiting the market as well. In order to advance scientific progress and expand the market, 2 SME's and 1 academic partner will combine their existing expertise and products for behavioural phenotyping to generate a compact modular system, INTELLIMAZE. This system should fit into a single small mouse room, where it will - Assess home cage activity and learning of transponder-tagged mice living in social groups - Analyse automatically social behaviour - Guide individual mice to a battery of traditionally used tests - Show ongoing learning on-line to a supervisor working in his office - Analyse data according to expert knowledge-based rules - Provide a web-based analysis of results for user groups. The bottleneck of such technological development is functional validation and comparison with traditional tests. Three academic partners will use the novel technology for a) generating new mouse models of depression, b) profiling malfunctions of specific brain systems, and c) monitoring the effects of age-dependent neurodegeneration in existing and new mouse models. Finally, an SME partner in need of efficient behavioural phenotyping will validate the novel systems for drug discovery and development. We expect that the availability of simplified, rapid and thorough behavioural testing of mice without need for specialized personnel will open new and larger markets for the SME's. Moreover we predict significant scientific discoveries in the fields of drug development, psychopharmacology, neurodegeneration, neural plasticity and repair, and genetic engineering.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy drug discovery
- medical and health sciences medical biotechnology genetic engineering
- medical and health sciences basic medicine physiology
- agricultural sciences animal and dairy science domestic animals animal husbandry
- medical and health sciences clinical medicine psychiatry schizophrenia
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-LIFESCIHEALTH-7
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
ZÜRICH
Switzerland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.