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Modelling brassinosteroid signalling in vascular development

Final Activity Report Summary - MOBSIV (Modelling brassinosteroid signalling in vascular development)

The main objective of the project is to untangle the role of BRs in vascular differentiation using Arabidopsis thaliana as a model system. The project analysed the contribution of the BR-responsive BRI1/BRL1 and BRI1/BRL3 pathways in setting up the proliferation and/or differentiation of xylem and phloem tissues from pluripotent vascular stem cells. To reach this objective, the project planned to use a multidisciplinary approach combining cell biology techniques, molecular genetics, plant physiology and genomics. Our final long-term goal is to bring together all the biological information obtained for the role of BRs in vascular development using a mathematical modelling approach thanks to the active collaboration that my host researcher has with Dr Marta Ibáñes, from the Physics Faculty of the University of Barcelona (UB), Spain.

To the major objectives of this research project are:
a) identification of BR-responsive genes involved in vascular development;
b) genetic dissection of the role of BRs in xylem and phloem differentiation;
c) hormone crosstalk in vascular development.