Objective
Reproduction is one of the most important events in an organism. In crops, it governs seed yields, viability and organoleptic properties. The regulation of reproduction happens in plants at the flowering stage.
Thus understanding of the whole process, including as initiation, signalling, growth and induction of second metabolites biosynthesis during flower development is necessary to clarify the mechanism of plant reproduction. Cytochrome P450 (P450) is one of the largest enzyme families in higher plant. P 450s are involved in the biosynthesis of various secondary metabolites related to defence responses or developmental events, as key monooxygenases.
In my host institution, a global P450 transcriptome analysis demonstrated that more than 120 P450 genes are expressed during flower development in Arabidopsis thaliana. Among them, five genes are expressed in the tapetum during the early stages of the pollen development. Three of these genes are activated upon insect attack. Thus their products might be involved in signalling and regulation of pollen development, or synthesis of physical barriers in higher plant.
My goal is to figure out 1) what is their biochemical substrate, and 2) what is the biological role of their products in plant development and defence. This will be achieved using existing silenced and over-expressing mutants of the genes of interest for metabolic profiling, analysis of the pollen structure and biology (viability, germination), and testing for insect resistance.
Completely successful work should establish a correlation between P450 expression, metabolic activity, pollen composition and properties, and variable defence response. It should therefore help understanding co-evolution of development and defence.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry metabolomes
- natural sciences biological sciences evolutionary biology
- natural sciences mathematics pure mathematics mathematical analysis functional analysis
- natural sciences chemical sciences organic chemistry amines
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-7
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
IIF - Marie Curie actions-Incoming International Fellowships
Coordinator
STRASBOURG
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.