Objective
The success of the Genome Projects carried out on a handful of model organisms has anticipated the extreme value of genomic comparative analyses as a way to unveil many functions and properties of these genomes. These analyses, anchored on an evolutionary framework, have the potential to explain the value of observed genomic differences in phenotype changes, with implications in research areas from biodiversity and speciation to health issues. However, given the unfeasibility to accomplish full genome studies in most or a good representation of life forms, alternative short-cut strategies have to be devised to grant access to genomic information of a wide variety of organisms and to assess the impact of their differences.
In this project, we propose the combined use of a PCR-based approach and Molecular Cytogenetics techniques (including FISH, M-FISH and Zoo-FISH), coupled with the ability to isolate specific chromosomes using laser micro-dissection techniques, to generate high-resolution physical chromosome maps of selected organisms using genetic landmarks provided by cDNA libraries. These physical maps will be analysed comparatively to trace genomic structural changes over evolutionary periods. We will implement this methodology in the study of speciation and diversification processes in leaf beetles (Chrysomelidae) focusing in the analysis of the genomic changes affecting chromosome structure at three different levels:
- role and constraints of hybridisation as a mechanism for speciation,
- chromosomal changes accompanying a species radiation, and,
- analysis of chromosome synteny in phytophagous Coleoptera.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences ecology ecosystems
- natural sciences biological sciences genetics chromosomes
- natural sciences biological sciences genetics genomes
- natural sciences physical sciences optics laser physics
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-11
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
MURCIA
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.