Objective
Dr. Trinidad Velasco, a Spanish national who has recently completed her PhD in the UK and been a researcher in Belgium in the area of bioorganic chemistry, is requesting funds for 2 years to research in Ireland with Dr. Paul Murphy and study fundamental aspects of the mechanism of action of multivalent legends. It is proposed that Trinidad will receive training in carbohydrate and oligosaccharide synthesis, application of NMR and molecular modelling techniques in design and determination of solution conformation of divalent legends and in biophysical methods for studying the interactions of the synthesised legends with biological receptors. Collaboration with the group of Hans Joachim Gabions and Sandrine Andre in Munich has recently been agreed. The project will diversify the expertise of the applicant who has worked previously on the area of supramolecular chemistry and molecular recognition of carbohydrates by synthetic macro cyclic receptors. This work provided a first approach to the principles of molecular design and the multiple interactions involved in carbohydrate recognition. The synthesis of a series of macro cyclic polyamide receptors was accomplished and the study of their binding properties both in homogeneous and heterogeneous media was carried out using a variety of techniques, such as NMR and fluorescence spectroscopy titrations and extraction experiments. The results obtained highlighted the importance of the precise disposition of the binding functionalities and the degree of conformational restriction in the receptors as fundamental factors in order to obtain selective and efficient monosaccharide recognition. During the course of her PhD, completed at the University of Bristol (UK), the applicant gained experience in synthetic organic chemistry procedures and a number of analytical techniques used to investigate supramolecular interactions between the studied hosts and guests.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences organic chemistry
- natural sciences earth and related environmental sciences geology mineralogy crystallography
- natural sciences physical sciences optics spectroscopy emission spectroscopy
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences biochemistry biomolecules carbohydrates
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-5
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
DUBLIN
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.