Objective
Small Ubiquity-related Modifier (SUMO) is a member of a ubiquity-like protein family that regulates cellular functions of a variety of target proteins. Whereas yeast have a single SUMO, essential for life, mammals have three, SUMO-1, -2 and -3. Whether they are all required, have overlapping functions and can complement or replace each other is currently unknown. Moreover, while SUMO-1 has been extensively studied, little is known about its two close homologues SUMO-2 and SUMO-3. In particular, no specific substrate for these is forms has-been found so far. Nevertheless SUMO-2 and SUMO-3 exhibit specific and important characteristics, the main one being their increased conjugation in response to various stresses. The objective of the proposed activity at the "Max Planck Institute" in Munich, Germany, under the supervision of Dr. Franker Melcher, is to study the functional differences between SUMO-1 and SUMO-2/3 is forms in normal and stress conditions. Joining Dr. Franker Melchers group will give me a unique opportunity to acquire new skills, especially in biochemistry, and participate to the emergence of this new field of biology that is ubiquity and ubiquitin-likeregulation of biological processes. The expertise I will obtain with Dr Melcher will be vital for carrying out my future career as independent researcher.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences zoology mammalogy
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-5
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
MUENCHEN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.