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Content archived on 2024-05-29

Structure-Function relationships in Prebiotic Oligosaccharides

Objective

The project aims to investigate the relationships between the structure of periodic oligosaccharides and their selective fermentation in the human gut. Specifically, the influence of molecular weight, monosaccharidecomposition and linkage type will be evaluated. Fermentation selectivity will be evaluated in faecal batch cultures using fluorescent in site hybridisation to monitor changes in bacterial populations. Data from such studies will bemuse to calculate a periodic index to allow quantitative comparisons of differing carbohydrate structures. Bacterial community profiles will be characterised by denaturing gradient gel electrophoresis. Bacterial metabolic end products such as short chain fatty acids and gas will be measured. To rationalise the metabolism of specificoligosaccharide structures, selected glycosidase enzymes will be isolated from gut bacteria and characterised. In addition, the presence of oligosaccharide transport systems will investigate. Information from the project will underpin functional food development activities around Europe and in several funded projects.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2002-MOBILITY-5
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

EIF - Marie Curie actions-Intra-European Fellowships

Coordinator

UNIVERSITY OF READING
EU contribution
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Address
Whiteknights House, Whiteknights
READING
United Kingdom

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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