Objective
Cancer is a European public health problem of overwhelming human and economic significance. There is now unimproved molecular understanding of the key genetic, biochemical and cellular changes leading to cancer, insignificant part due to the efforts of diverse groups of world-class EU-based scientists. With the completion of the human genome sequence imminent, it is now timely to initiate a major European co-ordinated effort to translate fundamental scientific knowledge about cancer into safer, more effective therapies and improved early diagnosticprocedures. The cellular immortality enzyme telemetries (one of the most promising universal cancer markers) and associatedtelomere maintenance mechanisms represent novel anti-cancer targets of enormous therapeutic and diagnostic potential. In MOL CANCER MED, we have established a multinational EU transactional cancer research consortium, in which talented cancer geneticists and molecular biologists will interact with prominent haematologists, clinicians and pathologists to develop these exciting new cellular targets into measurable pre-clinical advances, within a 3.5-year time-frame.
The Project has been structured into three, highly interactive Areas of Activity, involving the fundamental evaluation and pre-clinical validation of:
(i) TELOMERASE as a target for cancer treatment and diagnosis based on new molecular knowledge about its expression and function,
(ii) associated DOWNSTREAM TELOMERE MAINTENANCEMECHANISMS as additional targets for novel drug design, and
(iii) new ANTICANCER DRUGS based on these targets. The Consortium will bring to bear diverse and complementary technological know-how of considerable power to deliver the above primary objectives. Effective management will maximize synergies across MOL CANCERMED in order to produce genuine improvements in the design of new treatments that promise to be active against abroad spectrum of common human malignancies.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy drug discovery
- medical and health sciences health sciences public health
- medical and health sciences basic medicine medicinal chemistry
- medical and health sciences clinical medicine oncology
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-LIFESCIHEALTH
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
UXBRIDGE
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.