Objective
ENACT aims to identify markers of response and tumour antigens that associate with ovarian and prostate cancer and melanoma progression and resistance to immunotherapy. Prospective clinical material will be collected during the life of the programme and new and existing tumour tissue, PBMC and serum banks will be available for use in the study. This common resource of material will be distributed to partners for the immunological, genomic, biochemical and proteomic analysis of tumour cells and host response(s) to immunotherapy. The results will be subjected to bioinformatic analysis in the context of clinical outcome of vaccine-based immunotherapy trials from 5 European clinical centres. Analysis of the results in the context of gender, will allow prominent inter- and intra- tumour/host biomarkers to be identified and translated back into clinical practice. The combined clinical and scientific expertise of the consortium provides added value and links with two on- going 5th Framework cancer programmes that will allow immediate access to melanoma patient data, tumour tissue and cell lines. This study promotes interdisciplinary translational research, which will offer a leading role to partners in 3 Eastern European NAS countries and in SMEs, and will provide a unique technology and science-driven platform for future expansion. We (the consortium) have extensive experience in the management and operation of 3rd-5th Framework projects and this current programme of research builds on previous experience and collaboration by many of the partners, but also increases the repertoire of scientific expertise by the inclusion of new partners, whose research skills are complimentary to the aims of ENACT.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine oncology prostate cancer
- medical and health sciences clinical medicine oncology skin cancer melanoma
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
- medical and health sciences clinical medicine cardiology cardiovascular diseases
- medical and health sciences basic medicine immunology immunotherapy
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-LIFESCIHEALTH
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NOTTINGHAM
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.