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European Membrane Protein Consortium

Objective

E-MeP's research platform will focus on developing and implementing new technologies to solve the bottlenecks that preclude the determination, at high throughput, of high-resolution structures of membrane proteins and membrane protein complexes. This will be achieved by integrating the activities of many of the world leaders in membrane protein structural biology. The E-MeP consortium will develop methods and exchange laboratory and in silico tools aimed at solving the structures of membrane proteins, which comprise more than 30% of known proteomes. Specifically, the heterologous production, purification and crystallisation of a library of bioinformatically-selected membrane proteins will be streamlined by elucidating the parameters responsible for success and failure at each of these key stages. In the process new technologies will be developed and commercialised to overcome existing bottlenecks peculiar to membrane protein structural genomics, which cannot be solved by existing methods. A mobilisation of European expertise to address this timely issue will ultimately contribute to understanding membrane protein-related human diseases.

Call for proposal

FP6-2002-LIFESCIHEALTH
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Coordinator

ASTON UNIVERSITY
Address
Aston Triangle
Birmingham
United Kingdom

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Participants (19)

BIOXTAL SA
France
Address
4 Rte De La Noue
Gif-sur-yvette

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CHALMERS TEKNISKA HÖGSKOLA AB
Sweden
Address

Gothenburg

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ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE
Switzerland
Address
Epfl
Lausanne

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GROUPEMENT D'INTERET ECONOMIQUE: CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE
France
Address
1, Rue Laurent Fries
Illkirch

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GÖTEBORGS UNIVERSITET
Sweden
Address
Vasaparken
Göteborg

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IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
United Kingdom
Address
Exhibition Road
London

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KAROLINSKA INSTITUTET
Sweden
Address

Stockholm

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MARTIN-LUTHER-UNIVERSITÄT HALLE-WITTENBERG
Germany
Address
Universitätsplatz 10
Halle (Saale)

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MAX-PLANCK-INSTITUT FUR BIOPHYSIK
Germany
Address
Marie-curie-str- 15
Frankfurt

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MEDICAL RESEARCH COUNCIL
United Kingdom
Address
20 Park Crescent
London

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Links
PHILIPPS-UNIVERSITAET MARBURG
Germany
Address
Biegenstrasse 10
Marburg

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STICHTING KATHOLIEKE UNIVERSITEIT, MORE PARTICULARLY: UNIVERSITY MEDICAL CENTRE NIJMEGEN
Netherlands
Address
Geert Grooteplein 10
Nijmegen

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STOCKHOLMS UNIVERSITET
Sweden
Address

Stockholm

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THE EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
Address
Meyerhosstrasse 1
Heidelberg

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THE UNIVERSITY OF BRISTOL
United Kingdom
Address
Senate House, Tyndall Avenue
Bristol

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THE UNIVERSITY OF GLASGOW
United Kingdom
Address
University Ave
Glasgow

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THE UNIVERSITY OF LEEDS
United Kingdom
Address
Woodhouse Lane
Leeds

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UNIVERSITY OF GRONINGEN
Netherlands
Address
Broerstraat 5
Groningen

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UNIVERSITÉ DE LA MEDITERRANÉE, AIX-MARSEILLE 2
France
Address
Boulevard Charles Livon, 58
Marseille

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