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Electronic Immuno-Interfaces and Surface Nanobiotechnology: A Heterodoxical Approach.

Objective

Molecular events occurring at the Nan scale impact on the macroscopic level in many different areas and rules for controlled manufacture at the Nan scale are important to understand. The ELISHA project is designed to improve knowledge in molecular interfaces and enable manufacture of new sensors, by interrogating the formation and signal generation of antibodies and electro conductive surfaces. The project is based on:
1) a proven series of experimental observations that antibody loaded electro conductive matrices give concentration dependant responses when interrogated with DC pulsed and AC impedance electronics and
2) the knowledge and belief that the project will bring breakthroughs in Nan scale interfacial electrochemistry, leading to novel generic platforms for electro-interfaced-immunosensors to be produced and commercialised. This is the primary objective of the NMP work programme, "to promote real breakthroughs, based on scientific and technical excellence". The project targets several priority areas in Nan technology, NMP-2002-3.4.1.2.1.'the interface between biological and non-biological entities' and NMP-2002-3.4.4.3 - 'New generations of sensors, actuators and systems for safety and security of people and environment'. Novel materials are expected, NMP-2002- 3.4.2.3.1. And the project is directly in the area of Nan biotechnology, NMP-1.2. The project goes beyond the 'state of the art' in many areas and will give significant strategic impact for the EU, addressing community societal objectives by producing new methods to rapidly detect
1) cancer markers,
2) fluoroquinolines antibiotics and
3) prison type peptides, enabling rapid and point of care detection. The project is structured into 9 work packages including antibody production, sensor fabrication, immobilisation methods, signal generation and electronics production. A prototype instrument is the material deliverable. A world class team of 9 partners has been brought together to make ELISHA a reality.

Call for proposal

FP6-2002-NMP-1
See other projects for this call

Funding Scheme

STREP - Specific Targeted Research Project

Coordinator

UNIVERSITY OF LEEDS
Address
Woodhouse Lane
Leeds
United Kingdom

Participants (8)

CRANFIELD UNIVERSITY
United Kingdom
Address
Cranfield
Bedford
ECOLE CENTRALE DE LYON
France
Address
Avenue Guy De Collongue 36
Ecully
TECHNISCHE UNIVERSITAET MUENCHEN
Germany
Address
Arcisstrasse 21
Muenchen
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland
Address
Western Road, Presentation Buildings
Cork
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain
Address
Serrano 117
Madrid
UNISCAN INSTRUMENTS LTD
United Kingdom
Address
Sigma House, Burlow Road
Buxton
UNIVERSITE JOSEPH FOURIER
France
Address
621 Avenue Centrale
Grenoble
TECHNOLOGY TRANSLATORS LIMITED
United Kingdom
Address
461 Aberford Road, Stanley
Wakefield