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Molecular Machines - Design the Nano-Scale Handling of Biological Antetypes the Artificial Mimics

Objective

We propose the set-up of a cross-disciplinary research initiative dealing with molecular machines, in particular biological and artificial motors. A close collaboration between chemists known for their expertise in designing functional (bio) molecular motors, biophysicists experienced in dealing with molecular bio machines and physicists with an excellent background in experimental techniques addressing single molecules will advance the basic understanding in this domain to be employed for the steering of molecular engines in the nanometre regime. State-of-the-art theoretical calculations will guide the experimental work and allow for its in-depth interpretation. The objective of the project is to develop new concepts and advance research tools to master the challenge of handling engines-engines at the single-molecule level. We expect that the implementation and integration of the complementary scientific approaches within the consortium will lead to synergetic research achievements. While biological systems are abundant in nature, their fuelling relies mostly on specific chemical reaction schemes and environments. On the other hand, synthetic chemists represented in the consortium have met the challenge of the design of functional artificial molecular motors. Of particular interest is the fact, that de novo designed artificial engines are frequently photo-physically and/or electrically driven, i.e., the corresponding fuelling systems can be integrated in single-molecule experimental set-ups. The long-term vision of our research initiative is, firstly, to merge the advantages of the accessible biological and artificial systems by (self-) assembling of hybrid bioinorganic working devices and, secondly, to rationalize and to operate them on the single-molecule level.

Field of science

  • /natural sciences/chemical sciences/organic chemistry/amines

Call for proposal

FP6-2002-NMP-1
See other projects for this call

Funding Scheme

STREP - Specific Targeted Research Project

Coordinator

FORSCHUNGSZENTRUM KARLSRUHE GMBH
Address
Weberstr. 5
Karlsruhe
Germany

Participants (9)

UNIVERSITA DI BOLOGNA
Italy
Address
Via Zamboni 33
Bologna
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Switzerland
Address
Ecublens
Lausanne
TECHNISCHE UNIVERSITEIT DELFT
Netherlands
Address
Julianalaan 134
Delft
MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.
Germany
Address
Hofgartenstrasse 8
Muenchen
TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands
Address
Den Dolech 2
Eindhoven
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland
Address
Raemistrasse 101
Zurich
INSTITUT CURIE
France
Address
26, Rue D'ulm
Paris
UNIVERSITE LOUIS PASTEUR
France
Address
Rue Blaise Pascal 4
Strasbourg
STICHTING VOOR FUNDAMENTEEL ONDERZOEK DER MATERIE - FOM
Netherlands
Address
Van Vollenhovenlaan 659
Utrecht