Objective
The aim of INTERACTION PROTEOME is to establish Europe as the international scientific leader in functional proteomics, i.e. in the analysis of protein-protein interactions. Major objectives include the establishment of a broadly applicable platform of routine methods for the analysis of protein interaction networks. A multidisciplinary appoach is laid out to address different aspects of the generation of protein-interaction data; their validation by cell biological, biochemical and biophysical methods; their collection in a new type of public database; and their exploitation and use for in silico simulations of protein-interaction networks. INTERACTION PROTEOME will develop novel technology, including a high-end mass spectrometer with extremely large dynamic range, high density peptide arrays, and improved visualisation technology for light and electron microscopy. Using the novel technology, the interaction partners of more than 100 relevant protein domains and more than 3.000 peptides will be characterised. Data obtained in the project will be collected in an improved version of the European MINT database. In parallel, novel bioinformatics tools for the prediction of protein interactions and their relation to post-translational modifications will be created. Software for in silico modeling of protein interactions will be developed and validated with the projects model systems. Each of these objectives represents a substantial advance of the state of the art in these technologies. The innovations generated in INTERACTION PROTEOME thus will provide the basis for an efficient analysis and systems modeling of fundamental biological processes in health and disease.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences software
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- natural sciences computer and information sciences databases
- natural sciences physical sciences optics microscopy electron microscopy
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-LIFESCIHEALTH
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
MARTINSRIED
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.