Objective
The primary focus of LIPGEN is the interaction of nutrients and genotype in the metabolic syndrome. With access to a large prospective cohort followed biannually for 7 years and with hard clinical and nutritional data, a unique opportunity exists to determine diet-gene interaction in the development of the metabolic syndrome. To ascertain the responsiveness to dietary fat modification, a large multi-center dietary intervention study will examine how diets varying in both fat content and composition influence insulin sensitivity and other aspects of the metabolic syndrome including gene intervantions. Parallel studies at molecular, cell and whole body level will investigate mechanisms linking dietary fat and the metabolic syndrome. A key aim of the animal nutrition component is to reduce saturated fat and increasing monounsaturated fatty acids (MUFA) and n-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA), whilst avoiding an increase in trans fatty acid intake. The objective of the plant biotechnology section is in the area of metabolic engineering of linseed, using marine algal genes to transgenically reconstitute the LC-PUFA biosynthetic pathway. These studies will be accompanied by a detailed economic analysis of the health costs of the metabolic syndrome across the EU and the implications of indivdual drug versus population nutrition intervention. It wil also look at the cost implications of implementing the new animal nutrition and plant biotechnologies in primary food production. Consumer attitudes to new agro-food technologies and the use of genomics in personalized nutrition will also be examined. Finally, a demonstrations project will show how in practice these fat-modified foods can be created and be used to reduce the risk facators of the metabolic syndrome. A major dissemination programme will target consumers, industry, opinion formers and SMEs.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology industrial biotechnology metabolic engineering
- medical and health sciences health sciences public health
- medical and health sciences clinical medicine endocrinology diabetes
- natural sciences biological sciences biochemistry biomolecules lipids
- medical and health sciences health sciences nutrition obesity
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-FOOD-1
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
DUBLIN
Ireland
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Participants (21)
217 READING
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P.O Box 1072 OSLO
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7800 BERGEN
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PARIS
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616 MAASTRICHT
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CORDOBA
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KRAKOW
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256 UPPSALA
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ROTTERDAM
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LUDWIGSHAFEN
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P.O Box 373 YORK
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ABERDEEN
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JOKIOINEN
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PARIS
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COLERAINE
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PORTO
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LONDON
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OXFORD
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MAIDENHEAD
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DUBLIN
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VLAARDINGEN
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