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New applications for compatible solutes from Extremophiles (HOTSOLUTES)

Objective

As life sciences and bioindustry enter a new era where biopreservation and manipulation are everyday concerns, in has become imperative to look for new and safer solutions to efficiently stabilize biomaterials.

Compatible solutes from hyperthermophilic bacteria, called hypersolutes, are superior to their mesophilic counterparts in the preservation of the performance of a wide variety of biomaterials, ranging from proteins to whole cells, skin, and artificial tissues. In both an economical and scientific points of view, the rapid development and discovery of new such compounds makes it urgent to unravel their potentialities.

The goal of the HOTSOLUTES project is to find hypersolute applications in old and emerging areas of research, ranging from classical Molecular Genetics to emerging approaches such as Genomics and Proteomics.

Within HOTSOLUTES, a group of experienced RTD research groups will concertedly work with SMEs with the intent of finding applications within the areas of Protein Stabilization and Aggregation, DNA and Protein Microarrays, Molecular Biology Enzyme Performance, Biosensor Technology, Heterologous Protein-Production Systems, and Animal Cell Line Stabilization.

The project will ultimately have a positive impact on diverse areas from basic sciences to health. HOTSOLUTES will hopefully contribute for the development of science best practice and European SME welfare.

Call for proposal

FP6-2003-INNOV-1
See other projects for this call

Funding Scheme

Cooperative - SMEs-Co-operative research contracts

Coordinator

STAB VIDA, INVESTIGACAO E SERVICOS EM CIENCIAS BIOLOGICAS LDA
Address
St Antonio De Oeiras
Oeiras
Portugal

Participants (9)

BITOP - AKTIENGESELLSCHAFT FUER BIOTECHNISCHE OPTIMIERUNG
Germany
Address
Stockumer Strasse 28
Witten
ASPER BIOTECH LTD.
Estonia
Address
Oru 3
Tartu
EMPRESA DE CONSULTORIA EM BIOTECNOLOGIA LDA
Portugal
Address
Av. Da Republica E.a.n. Edificio Itqb/ibet - Laboratorio 4.11
Oeiras
TRENZYME GMBH
Germany
Address
Glockenbrunnenstr. 12
Konstanz
BIOANALYTICAL TECHNOLOGIES
Russia
Address
Shabolovka 12
Moscow
INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA
Portugal
Address
Avenida Da Republica, Estacao Agronomica Nacional
Oeiras
CENTRO DE NEUROSCIENCIAS DE COIMBRA
Portugal
Address
Departamento De Zoologia, Universidade De Coimbra
Coimbra
UNIVERSITA DEGLI STUDI DI FERRARA
Italy
Address
Via Savonarola 9
Ferrara
CRANFIELD UNIVERSITY
United Kingdom
Address
Silsoe
Cranfield, Bedford