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New applications for compatible solutes from Extremophiles (HOTSOLUTES)

Objective

As life sciences and bioindustry enter a new era where biopreservation and manipulation are everyday concerns, in has become imperative to look for new and safer solutions to efficiently stabilize biomaterials.

Compatible solutes from hyperthermophilic bacteria, called hypersolutes, are superior to their mesophilic counterparts in the preservation of the performance of a wide variety of biomaterials, ranging from proteins to whole cells, skin, and artificial tissues. In both an economical and scientific points of view, the rapid development and discovery of new such compounds makes it urgent to unravel their potentialities.

The goal of the HOTSOLUTES project is to find hypersolute applications in old and emerging areas of research, ranging from classical Molecular Genetics to emerging approaches such as Genomics and Proteomics.

Within HOTSOLUTES, a group of experienced RTD research groups will concertedly work with SMEs with the intent of finding applications within the areas of Protein Stabilization and Aggregation, DNA and Protein Microarrays, Molecular Biology Enzyme Performance, Biosensor Technology, Heterologous Protein-Production Systems, and Animal Cell Line Stabilization.

The project will ultimately have a positive impact on diverse areas from basic sciences to health. HOTSOLUTES will hopefully contribute for the development of science best practice and European SME welfare.

Call for proposal

FP6-2003-INNOV-1
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Coordinator

STAB VIDA, INVESTIGACAO E SERVICOS EM CIENCIAS BIOLOGICAS LDA
Address
St Antonio De Oeiras
Oeiras
Portugal

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Participants (9)

BITOP - AKTIENGESELLSCHAFT FUER BIOTECHNISCHE OPTIMIERUNG
Germany
Address
Stockumer Strasse 28
Witten

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ASPER BIOTECH LTD.
Estonia
Address
Oru 3
Tartu

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EMPRESA DE CONSULTORIA EM BIOTECNOLOGIA LDA
Portugal
Address
Av. Da Republica E.a.n. Edificio Itqb/ibet - Laboratorio 4.11
Oeiras

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TRENZYME GMBH
Germany
Address
Glockenbrunnenstr. 12
Konstanz

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BIOANALYTICAL TECHNOLOGIES
Russia
Address
Shabolovka 12
Moscow

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INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA
Portugal
Address
Avenida Da Republica, Estacao Agronomica Nacional
Oeiras

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CENTRO DE NEUROSCIENCIAS DE COIMBRA
Portugal
Address
Departamento De Zoologia, Universidade De Coimbra
Coimbra

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UNIVERSITA DEGLI STUDI DI FERRARA
Italy
Address
Via Savonarola 9
Ferrara

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CRANFIELD UNIVERSITY
United Kingdom
Address
Silsoe
Cranfield, Bedford

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