Objective
Heart disease is a major cause of death in the Western world. In the past three decades there have been a number of improvements in artificial devices and surgical techniques for cardiovascular disease; however there is still aneed for novel devices, espec ially for those individuals who cannot receive conventional therapy. The major disadvantage of current artificial devices lies in the fact that they cannot grow, remodel or repair in vivo. Tissue engineering offers the possibility of developing a biologica l substitute material in vitro with the inherent mechanical, chemical, biological and morphological properties required in vivo, on an individual patient basis.In order to develop a true biological cardiovascular device a dynamic physiological environment needs to becreated. The main objective of this research is to develop a physiological simulator capable of mimicking the in-vivo biological, biomechanical and biochemical conditions of the cardiovascular system in-vitro, to predict the biological and mecha nical response of conventional and novel tissue engineered cardiovascular materials invivo. In parallel computational modelling will be applied to predict local cell deformations and models generated will be correlated and assessed with experimental deform ations and biological responses. The results of this study if successful will represent a significant scientific breakthrough, paving the way for future generations of functional biological replacement materials, capable of restructuring and remodelling in -vivo. Thereby, offering the possibility of helping thousands of people who suffer from cardiovascular disease.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences medical biotechnology tissue engineering
- medical and health sciences clinical medicine cardiology cardiovascular diseases
- engineering and technology industrial biotechnology biomaterials
- natural sciences mathematics applied mathematics mathematical model
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-3
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
GALWAY
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.