Objective
The proposed project is an investigation of a newly discovered consortium comprising a novel group of SM1- Archaea and bacterium, mainly Thiothrix, that takes on the appearance of a string-of-pearls.
Objects bearing a close physical resemblance to these consortia have been found in rocks as old a 1500 million years and are presently considered 'problematic' fossils because there have been no known modern analogues for comparative study. In this project we will investigate the physiology and metabolism of the string-of-peals by investigating changes in their lipid biomarker compositions in response to exposure to different nutrients.
Our primary objective will be to follow the flow and fate of carbon through the consortium by feeding substrates labelled with s table isotope (13C) applied during growth in the natural environment. We expect the results will show the preferred carbon sources of the bacteria, as well as on the intra-consortium carbon transfer.
Furthermore, predictions on metabolic activity and growth rates are expected. The uptake of label into both organisms will be followed by analyses of extractable lipid biomarkers and other metabolic intermediates using gas chromatography-isotopic resolution mass spectrometry (GC-c-IRMS).
We will be able to determine the direction of carbon flow by establishing which compounds are labelled first and because bacterial and archaeal lipids are readily distinguished on the basis of their chemical structures and because some preliminary analyses of the lipid contents.
If other, presently unknown, lipid biomarkers are found, their structures will be investigated using high resolution mass spectrometry and high pressure liquid chromatography mass spectrometry. This aspect will add to the knowledge base about lipid biomarker-organism associations.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences microbiology microbiomes
- natural sciences biological sciences biochemistry biomolecules lipids
- natural sciences chemical sciences analytical chemistry mass spectrometry
- natural sciences earth and related environmental sciences geochemistry organic geochemistry
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-6
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
OIF - Marie Curie actions-Outgoing International Fellowships
Coordinator
BREMEN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.