Objective
Severe Acute Respiratory Syndrome (SARS) is a life-threatening form of pneumonia caused by a novel coronavirus (SARS-CoV). The prevention and/or containment of future outbreaks will depend on our understanding of SARS-CoV biology, pathogenesis, and evolution. An overall strategy to combat this novel virus needs to be designed, in particular using reliable diagnostic tools, specific antiviral compounds, and a SARS-CoV vaccine. The SARS-DTV consortium consists of a balanced mixture of scientists that have worked on coronaviruses for most of their professional career and specialists in other fields. The expertise of the first group covers coronavirus molecular biology, evolution and immunology. Complementary expertise, and state of the art technology, is supplied by partners specialized in structural biology, B- and T- cell immunology, in vivo model sytems, diagnostics and drug screening. Also a number of Asian partners participate in the consortium to ensure access to SARS-CoV-related materials and a constant dialogue with researchers in the primary SARS-affected area of the world and its rapidly developing SARS research programme. The overall objective of the SARS-DTV network is to contribute to the development of candidate anti- SARS-CoV drugs, vaccines and diagnostic assays, by collaborative and complementary research divided into four Work packages. Molecular targets for anti-SARS-CoV therapy will be identified and characterised in terms of structure and function. (Bio)chemical approaches will identify "lead compounds" (candidate antiviral agents). The correlates of the humoral and cellularprotective anti-SARS-CoV immune response will be defined and the role of immunopathology in SARS will be addressed. The Model Systems work package aims to develop SARS- CoV reverse genetic systems as research tools and apply these to automated drug testing in the form of a bio- safe, cell culture-based screening system...
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine immunology
- medical and health sciences health sciences infectious diseases RNA viruses coronaviruses
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2003-SSP-2-SARS
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
9503 LEIDEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.