Objective
Harmful algal blooms (HABs) are caused by local proliferation of algae, with deleteriousconsequences, particularly in coastal waters throughout the world. Negativeenvironmental effects include toxicity to human consumers of seafood, marine faunalmortalities or morbidity, habitat damage, disruption of marine food webs and economiclosses to fishing, aquaculture, and tourism. In Europe, socio-economic factors andhuman health risk have led to comprehensive surveillance programmes for harmfulmicroalgae and their toxins. Among harmful microalgae and cyanobacteria in Europeanmarine and brackish waters, many produce potent neurotoxins, ichthyotoxins orhepatotoxins. Although structural elucidation of many of these groups of toxins hasadvanced, much less is known about biosynthetic pathways and gene regulation intoxigenic species. We propose a limited genomic study of expressed sequence tags(ESTs) for toxigenic representatives of major eukaryotic microalgal groups, includingdinoflagellates, raphidophytes, prymnesiophytes and diatoms, and cyanobacteria.Cultures will be grown under various environmental conditions to investigate the effectsof external forcing functions on gene expression linked to toxicity and growth. Aftercloning of cDNA of toxigenic strains pooled from cultures grown under these differentconditions into plasmid vectors, about 10,000 clones from each taxon will be randomlysequenced for ESTs. Our approach is to annotate ESTs and attempt identification ofgenes associated with toxin production, growth regulation, cell cycle, stress responsesand induction of sexuality. DNA microarrays will be developed for analyse the geneexpression of the differently treated cultures. Successful completion of this project willyield new information on microalgal and cyanobacterial genomic sequences for adiversity of taxa and will assist in the diagnosis of genes related to toxin biosynthesis.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- agricultural sciences agriculture, forestry, and fisheries fisheries
- natural sciences biological sciences microbiology phycology
- natural sciences biological sciences genetics DNA
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Data not available
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2003-GLOBAL-2
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
160121 BREMERHAVEN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.