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Content archived on 2024-05-29

A prospective analysis of the mechanisms of nuclear hormone receptors and their potential as tools for the assessment of developmental toxicity

Objective

In view of developing an innovative non-animal test method for chemicals, medicines, biological and bio-materials, the proposed project has the final goal of producing a prospective analysis of the mechanisms of nuclear hormone receptors and their potential as tools for the assessment of developmental toxicity. The prospective analysis will either define a practical research programme for future RDT activities in this field, or conclude that the area is not sufficiently mature at present time. The specific objectives of the project are the following: - To investigate the role of nuclear hormone receptors in developmental and reproductive biology and to review the state of the science in this field; - To define a practical research programme with the aim of enhancing knowledge on the mechanisms of developmental toxicity and the role of nuclear receptors in the process; - To develop a plan aimed at applying such understanding to the future assessment of the relevance of in vitro systems as predictive models for developmental toxicity. The project, proposed as an SSA, consists of two workshops where the best European research resources in the area of molecular biology, genomics and developmental toxicology will be pooled together with the aim of investigating the role of nuclear hormone receptors in developmental and reproductive biology.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2003-LIFESCIHEALTH-I
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

SSA - Specific Support Action

Coordinator

EXXONMOBIL PETROLEUM & CHEMICAL
EU contribution
No data
Address
Polderdijkweg
ANTWERPEN
Belgium

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (8)

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