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Content archived on 2024-05-29

Pathogenesis of pulmonary disease

Objective

Exposure of the lung surface to air-born pollutants or other toxic/ infectious agents causes reactions at the air-liquid interface, the immune system, the epithelial barrier and adjacent tissue. This may result in acute and/or chronic diseases, representin g an increasing socio-economic burden to the European Community. Their underlying pathogenetic mechanisms involve physico-chemical events, such as air-liquid interface phenomena, and cellular events, such as immune defense, secretion, transport and barrier (dys)functions. The further elucidation of the pathogenesis of pulmonary disease will be achieved only if an integrated research approach is undertaken. This will need to encompass biophysical, biochemical, (patho)physiological and immunological events ta king place in a narrow space. The proposed RTN is headed by top scientists in these diverse but complementary fields of basic pulmonary biology and offers excellent training opportunities. It will provide a structured training program for early-stage and e xperienced researchers and increase the number of broadly trained expert pulmonary scientists exposed to different ¿schools of thought¿ and needed for new developments in pulmonology. Extensive transfer of knowledge will enhance methodological progress and exchange of research tools/ideas needed to develop miniaturized organ systems for in vitro pulmonary toxicity testing, and to define endpoint parameters for lung damage. This will provide a basis for new therapeutic approaches, the identification of risk factors, the prevention of disease and a diminished need for animal experiments. The participation of a SME and the strong connections between the university partners and pharmaceutical and other companies will provide training in intellectual property and entrepreneurial issues. A unique postgraduate program in Pulmonary Biology, developed in this project, will ensure sustainability of the project and the creation of a training center of excellence.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2002-MOBILITY-1
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

RTN - Marie Curie actions-Research Training Networks

Coordinator

UNIVERSITÄTSKLINIKUM ULM
EU contribution
No data
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (6)

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