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Human exposure to particulate matter and source-to-internal dose relationships

Objetivo

The objective of the proposed Marie Curie action is the understanding of the particulate matter (PM) transport into the human body and the quantification of the internally PM deposited regional dose in the human respiratory tract, and the consequent transport into the human organs. In addition, another objective is the understanding of the formation, accumulation, fate and effects of ozone, other photochemical oxidants and fine particulate matter in the southern-eastern part of the Mediterranean area.

The specific objectives of the proposed Marie Curie action are to link human exposure to particulate matter with physiologically based mechanistic dosimetry, clearance and transfer inside the human body models. The mechanistic respiratory dosimetry model which is in use at the Technical University of Crete (Lazaridis et al., 2001) for particulate matter will be further improved with the addition of state-of-the-science modelling tools of particulate matter clearance inside the human respiratory track an transport into the blood, the regional lymph nodes and the gastrointestinal part. Furthermore, other specific objectives include the measurements of gaseous and aerosol species in the eastern part of the Mediterranean area.

Ámbito científico (EuroSciVoc)

Palabras clave

Tema(s)

Convocatoria de propuestas

FP6-2002-MOBILITY-3
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Régimen de financiación

TOK - Marie Curie actions-Transfer of Knowledge

Coordinador

TECHNICAL UNIVERSITY OF CRETE
Aportación de la UE
Sin datos
Coste total
Sin datos