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Content archived on 2024-06-16

Food and Fecundity: Pharmaceutical Products as high risk effectors.

Objective

Over recent years there has been a growing interest in the declines in human fecundity. Since many chemicals have been shown experimentally to mimic the activities of reproductive hormones, the potential exists that exposure to environmental chemicals has an influence on human reproductive endpoints. A particular aspect that has received relatively sparse attention is the extent to which food as a medium for exposure to synthetic endocrine disrupters impacts on human fecundity. So far, studies focused mainly on the ventional endocrine disruptors: pesticides, heavy metals and toxic environmental taminants of industrial origin. One large class of chemical that received little attention is that of pharmaceutical products (PPs), which are used in quantities comparable to those of agrochemicals. Currently, very little is known of the occurrence, fate and effects of PPs in the environment. Our understanding of the possible transmission of PPs into the food chain is also very scarce and even less is known on how such food affects human fecundity. Part of the problem results from the scarcity of methods for simple and efficient clean up and centration, and from the lack of high-throughput low-cost diagnostic assays. In this project we intend to integrate research groups from different disciplines for a better understanding of the extent of the problem. The strategic approach of the project is to develop methods for screening PPs, and their metabolites, to determine their adverse effects, origin and fate, as well as their mechanisms of action, assess their risk and propose risk management policies. These methods, once developed and validated should identify and characterize the endocrine activity of PPs, enable to point at PP compounds that affect fecundity, present the information to the public via knowledge pools, and help in determining methods to prevent or minimize these risks.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2003-FOOD-2-A
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

STREP - Specific Targeted Research Project

Coordinator

ANALYST RESEARCH LABORATORIES LTD.
EU contribution
No data
Address
Hamada Street 12, Rabin Park
REHOVOT
Israel

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Total cost

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No data

Participants (8)

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