Objective
In this STREP we will study the multifaceted interactions between genetic and nutritional factors that may influence sexual maturationThe major objectives of PIONEER are to: 1) obtain updated scientific data on the age of puberty onset in the different regions of Europe.2) identify some genetic and nutritional factors involved in the regulation of the onset of puberty, with special reference to their interactions.3) develop novel experimental test models, including in vivo animal models, optimized for the investigation of genetic and nutritional factors regulating onset of puberty.4)define if specific actions are necessary within EU, to avoid children from maturing too early sexually.The factors that induce early sexual maturation in children are largely unknown. Multiple etiological factors are involved, including both genetic, and environmental and life-style factors, and their complex interactions. Genetic background plays a major role in determining the timing of puberty. Therefore, for understanding role of nutritional factors, it is of paramount importance to know, which individuals have the genetic susceptibility to environmental factors, which may cause early maturation. Clearly, a multidisciplinary approach is required toachieve these objectives. A consortium with a wide range of expertise in clinical and experimental sciences has been established. With regard to the nutritional influences, we will focus on two major questions: i) the impact of nutritional excess and obesity on puberty onset, and ii) the influence of selected endocrine disrupting compounds. Furthermore, we will give emphasis to the development of novel in vivo test models that, because of the complexity of the phenomenon, are clearly needed. With this approach PIONEER will help to identify genetic subpopulations that may be at high risk for early sexual maturation and develop novel experimental test models, needed for the development of preventive strategies.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2003-FOOD-2-A
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
TURKU
Finland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.