Objective
With the recent ban on the use of compounds such as malachite green in food fish production, there is an urgent need to find suitable efficacious compounds to control certain fish pathogens. There is also a need to improve fish health and reduce the dependency on drugs by assessing the utility of natural products as possible replacements. One potential group, the bio-flavonoids, comprise a vast array of biologically active compounds that are ubiquitous in plants. They display an incredible array of biochemic al and pharmacological actions (anti-inflammatory, anti-oxidant, anti-allergic, anti-viral & anti-carcinogenic).
Their use in human and veterinary medicine (e.g. to control viruses in HIV/AIDS patients, in the study of coronary and circulatory disease and, as a topical spray to control MRSA in hospitals) is being actively researched. Unfortunately, almost nothing is known of the action of bioflavonoids on the immune system of fish. The project will assess the efficacy of selected bioflavonoids, as potential biocides and immuno-stimulants, in their ability to control bacterial and protozoan parasitic infections following experimental challenge.
The project will screen a large number of bioflavonoids in vitro against several main fish pathogens to assess their biocidal activity before testing the most promising candidates in vivo to ascertain if they also have an immunostimulatory effect. The pathogens that will be screened include the pathogenic bacteriums Vibrio anguillarum, Aeromonas hydrophila and Renibact erium salmoninarum, the causative agent of Bacterial Kidney Disease, a notifiable fish pathogen within Europe.
Their efficacy against the parasitic protozoan Ichthyophthirius multifiliis one of the most pathogenic diseases of freshwater fishes will also be tested. Examining complex interactions between food intake and the metabolism of bioflavonoids in the control of pathogens of fish and their effect on the immune system will make a significant contribution.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- agricultural sciences agriculture, forestry, and fisheries fisheries
- engineering and technology other engineering and technologies food technology food safety
- natural sciences biological sciences zoology ichthyology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-7
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
IIF - Marie Curie actions-Incoming International Fellowships
Coordinator
STIRLING
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.