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Active biomimetic systems

Objective

The STREP proposed here deals with biomimetics at the supramolecular or subcellular level which covers the nano- and microregime. In this regime, biological systems exhibit many active processes which are driven by a variety of biomolecular nanomaschines o r motors. The biomimetic systems studied in this STREP contain two types of linear motors, growing filaments and stepping motor proteins. Growing filaments generate pushing forces, stepping motor proteins exert pulling forces. The project has several scien tific objectives: to understand the molecular processes which are responsible for the generation of these forces; to elucidate the cooperative behavior of small and large groups of motor molecules which lead to active surface layers and active filament ass emblies or scaffolds; and to control and optimize the properties of these biomimetic systems. The research performed in this STREP is at the cutting edge of science and has a high potential for long-term innovation. Indeed, there are many possible applicat ions in bioengineering, pharmocology, and medicine such as sorting devices for biomolecules and biocolloids, active drug delivery systems, and force generating components for the development of nanoscale manufacturing.

Call for proposal

FP6-2003-NMP-TI-3-MAIN
See other projects for this call

Coordinator

MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
Address
Hofgartenstrasse 8
München
Germany

Participants (10)

BASF AKTIENGESELLSCHAFT
Germany
Address
Carl-bosch-strasse 38
Ludwigshafen
CENTRE NATIONAL DE LA RECHERCE SCIENTIFIQUE
France
Address
Avenue De La Terrasse
Gif-sur-yvette
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
Address
Meyerhofstrasse
Heidelberg
INSTITUT CURIE SECTION RECHERCHE
France
Address
26 Rue D'ulm'
Paris
INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES
China
Address
Zhong Guan Cun, Bei Yi Jie No 2
Beijing
LEIBNIZ INSTITUT FUER ALTERSFORSCHUNG - FRITZ LIPMANN INSTITUT E.V.
Germany
Address
Beutenbergstrasse 11
Jena
NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY
China
Address
Zhong Guan Cun, Bei Yi Tiao, 11
Beijing
POLITECNICO DI MILANO
Italy
Address
Piazza Leonardo Da Vinci 32
Milano
STICHTING FOM (FUNDAMENTEEL ONDERZOEK DER MATERIE)
Netherlands
Address
Van Vollenhovenlaan 659
Utrecht
UNIVERSITÄT LEIPZIG
Germany
Address
Linnéstrasse 5
Leipzig