Objective
Dengue, the most rapidly expanding viral disease in S-East Asia and Latin America, is a major neglected and uncontrolled disease. This project will provide new knowledge, tools and strategies in 3 key areas: 1. Improved knowledge of the immunopathology of severe dengue contributing to the development of a safe and efficacious vaccine and eventually to improved treatment 2. Improved case-management through a modified dengue case definition and treatment guidelines and eventually the identification of early w arning signs for severe disease 3. Improved protection from disease transmission by means of novel vector control tools which are applied through a new cost-effective strategy The specific objectives of the project are: 1.To create new knowledge about viru s genetic factors of virulence, immune response and pathophysiological mechanisms across regions (SE Asia and LA) relevant to clinical management of severe disease and vaccine development 2a) To obtain a clear distinction between dengue and severe dengue b y developing an evidence-based case classification procedure 2b) To develop case management guidelines that will use the revised case classification and subsequently reduce morbidity and mortality 3.To test novel vector control tools (long-lasting insectic ide treated curtains and/or water container overs and/or slow-release insect growth regulators) which reduce vector densities below epidemic threshold levels 4.To assess key strategies which deliver new vector control tools regarding their cost-effectivene ss,acceptability and sustainability in contrasting environments 5.To demonstrate and document the timely translation of research findings into policy and practice (clinical as well as control) The 5 work packages related to these objectives are designed by a multidisciplinary team of scientists from disease endemic countries in SE Asia, LA and from Europe.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- social sciences sociology demography mortality
- medical and health sciences basic medicine immunology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2003-INCO-DEV-2
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
HEIDELBERG
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.