Objective
Aquaculture is growing more rapidly than all other animal food producing sectors. Bivalve culture is steadingly growing in importance in the aquaculture of many European Union Member States. However, even though several bivalve diseases produce significant economic loses, no effective tools to fight against infectious diseases are available, and the knowledge on the immune mechanisms developed against infectious is very limited.
The main goal of this project is the characterization of pathology and the host-parasite relationships at ultra-structural level produced by the most important pathogens identified in the aqua-cultured bivalve molluscs, bacteria (Vibrio sp.) and parasites (Bonamia ostreae and Perkinsus atlanticus parasites of oysters Ostrea edulis and clams Ruditapes decussatus respectively) at different times of infection. In addition, the molecular basis of mollusc immune response developed against the infections will be studied. Cellular and humoral parameters, as well as oxygen and nitrogen free radicals production and antioxidant enzymes will be characterized in vitro.
The presence and location of enzymes associated to defence mechanism will be analysed by TEM immuno cytochemistry. The identification and characterization of new genes involved on the immune response of the bivalve molluscs against infections will be carried out. Once the genes are identified, recombinant proteins will be produced and their effect in bivalve mollusc immune function will be determined. The project will be centred in genes with immune relevance, specifically those involved in the expression of cytokine like molecules. The characterisation of immune genes with relevant role in immune defence can lead to identify marker genes that could later be used in the selection for resistance to the diseases of bivalve populations.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- agricultural sciences agriculture, forestry, and fisheries fisheries
- medical and health sciences health sciences infectious diseases
- medical and health sciences basic medicine immunology
- medical and health sciences basic medicine pathology
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-11
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
MADRID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.