Objective
The knowledge generated by the sequencing of the human genome will enable the development of more effective strategies for preventing, diagnosing and treating human diseases, and consequently decrease morbidity and mortality. One can therefore anticipate that children should benefit from advances of the genome era.
Application of advances in genomics, biotechnology and therapeutics to provide children with more efficacious and safer medicines will require the development of a new research matrix that integrates scientific domains, assesses impact of findings and implements policies. Furthermore, any attempt to integrate genetic information into medical practice ought to consider human development and maturation, from the prenatal period through adolescence.
TEDDY project is aimed at optimising the paediatric use of current drugs and promoting the development of new drugs, by incorporating pharmacogenetic applications and implementing guidance/tools to perform paediatric research. Special attention will be paid to variability in response, particularly, the role of gender factors and time-dependencies associated with the development from prenatal period to adolescence. A framework will be developed to characterise adverse drug reactions and optimise dosing regimens, including research projects on pharmacogenetic variants. Harmonised databases and guidelines will be created for marketed medicines. Training programmes on ethics, scientific and clinical skills will be set up to increase research capacity and promote social awareness.
The proposed network will include stakeholders in drug development and paediatric clinical practice. European academics, scientists, healthcare specialists and ethics experts will work together with pharmaceutical companies, regulatory agencies and patients associations to implement a common mission. A strong link with existing European networks running clinical trials in children, such as PENTA and PRINTO, will be established.
Fields of science
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery
- social sciencessociologydemographymortality
- natural sciencescomputer and information sciencesdatabases
- medical and health sciencesbasic medicinepharmacology and pharmacyadverse drug reactions
- natural sciencesbiological sciencesgeneticsgenomes
Call for proposal
FP6-2003-LIFESCIHEALTH-I
See other projects for this call
Funding Scheme
NoE - Network of ExcellenceCoordinator
PAVIA
Italy
See on map
Participants (18)
PADOVA
See on map
LONDON
See on map
9502 LEIDEN
See on map
POBOX 1738 ROTTERDAM
See on map
ROMA
See on map
BUCHAREST
See on map
LINKÖPING
See on map
PARIS
See on map
LONDON
See on map
MADRID
See on map
LIÈGE
See on map
PRAGUE 4
See on map
HAIFA
See on map
BERLIN
See on map
193 POMEZIA (RM)
See on map
LONDON
See on map
BARI
See on map
SEGRATE
See on map