Objective
Assessing individual exposure to environmental stressors and predicting health outcomes implies that both environmental exposures and epi/genetic variations are reliably measured simultaneously. HEALS (Health and Environment-wide Associations based on Large population Surveys) brings together in an innovative approach a comprehensive array of novel technologies, data analysis and modeling tools that support efficiently exposome studies. The general objective of HEALS is the refinement of an integrated methodology and the application of the corresponding analytical and computational tools for performing environment-wide association studies in support of EU-wide environment and health assessments. The exposome represents the totality of exposures from conception onwards, simultaneously identifying, characterizing and quantifying the exogenous and endogenous exposures and modifiable risk factors that predispose to and predict diseases throughout a person’s life span. The HEALS approach brings together and organizes environmental, socio-economic, exposure, biomarker and health effect data; in addition, it includes all the procedures and computational sequences necessary for applying advanced bioinformatics coupling thus effective data mining, biological and exposure modeling so as to ensure that environmental exposure-health associations are studied comprehensively. The overall approach will be verified and refined in a series of population studies across Europe including twin cohorts, tackling different levels of environmental exposure, age windows of exposure, and socio-economic and genetic variability. The HEALS approach will be applied in a pilot environment and health examination survey of children including singletons and sets of twins with matched singletons (each twins pair having also a matched singleton) covering ten EU Member States (the EXHES Study). The lessons learned will be translated into scientific advice towards the development of protocols and guidelines for the setting up of a larger European environment and health examination survey.
Programme(s)
Call for proposal
FP7-ENV-2013-two-stage
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Funding Scheme
CP - Collaborative project (generic)Coordinator
75006 Paris
France
Participants (36)
Participation ended
75252 Paris
54636 Thessaloniki
EH14 4AP Edinburgh
70174 Stuttgart
1000 Ljubljana
75270 cedex 06 Paris
BS8 1QU Bristol
00161 Roma
80539 Muenchen
91 348 Lodz
Participation ended
02044 VTT Espoo
02150 Espoo
M13 9PL Manchester
2595 DA Den Haag
Participation ended
SW1P 3JR London
28006 Madrid
50100 Kozani
08028 Barcelona
Participation ended
1049 001 Lisboa
Participation ended
10020 Zagreb
00185 Roma
4099-002 Porto
15341 Agia Paraskevi
43003 Tarragona
93053 Regensburg
Participation ended
2333 BZ Leiden
WC2R 2LS London
0456 Oslo
5230 Odense M
94607 Oakland Ca
17177 Stockholm
4200-465 Porto
EC2V 7NQ London
10000 Zagreb
8000 Aarhus C
2333 BZ Leiden