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BluePharmTrain

Objective

Marine sponges harbour extremely diverse populations of microbes, and are world record holders for the production of a plethora of bioactive molecules. Previous studies, however, aiming at the growth of sponges or their associated microbes for the production of bioactive compounds to supply biological material for clinical trials, have been largely unsuccessful.
BLUEPHARMTRAIN is a multi-disciplinary alliance of 20 academic and industrial partners that will excel in research and training through integration of complementary expertise in cell biology, microbiology, natural product chemistry, genomics & transcriptomics (omics) and socio-economics. We will adopt cutting-edge omics technologies to give a new boost to the more traditional disciplines: microbial isolation, cell culture and natural product chemistry to go beyond the current scientific frontiers. For example, metagenomic and transcriptomic data will be applied to identify the metabolic potential and restrictions of -yet- uncultured microbes and will serve for the design of tailor-made cultivation conditions. In addition, heterologous expression of bioactive gene clusters and enzymes able to perform unusual modifications will serve as an alternative strategy to unlock the bioactive potential of sponges. Thus we aim to develop an extensive technology platform that is applicable for obtaining a wide variety of bioactive compounds from distinct sponges and their microbes.
BLUEPHARMTRAIN will provide a complementary set of experimental and conceptual local and network-wide training modules and workshops to 15 young researchers. The recruited fellows will work towards personalized training plans to meet individual needs and interests, generating a critical mass of young researchers in the emerging field of blue biotechnology. The presence of a large consortium of versatile biotechnology, pharmaceutical and consultancy firms ensures a good balance between academic and transferable skills acquired by the fellows.

Field of science

  • /natural sciences/biological sciences/cell biology
  • /natural sciences/biological sciences/microbiology
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins/enzymes

Call for proposal

FP7-PEOPLE-2013-ITN
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

WAGENINGEN UNIVERSITY
Address
Droevendaalsesteeg 4
6708 PB Wageningen
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 052 176,62
Administrative Contact
Detmer Sipkema (Dr.)

Participants (10)

MATIS OHF
Iceland
EU contribution
€ 227 887
Address
Vinlandsleid 12
113 Reykjavik
Activity type
Research Organisations
Administrative Contact
Ragnar Johannsson (Dr.)
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 200 683,78
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
Administrative Contact
María ángeles López Vázquez (Ms.)
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland
EU contribution
€ 528 531,52
Address
Raemistrasse 101
8092 Zuerich
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Joern Piel (Prof.)
TALLINNA TEHNIKAULIKOOL
Estonia
EU contribution
€ 197 029,36
Address
Ehitajate Tee 5
12616 Tallinn
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Merike Kelve (Dr.)
CARDIFF UNIVERSITY
United Kingdom
EU contribution
€ 541 208,80
Address
Newport Road 30-36
CF24 ODE Cardiff
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Rebecca Blackwell (Mrs.)
HASKOLI ISLANDS
Iceland
EU contribution
€ 227 887
Address
Saemundargotu 2
101 Reykjavik
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Margret Thorsteinsdottir (Dr.)
RIJKSUNIVERSITEIT GRONINGEN
Netherlands
EU contribution
€ 242 361,46
Address
Broerstraat 5
9712CP Groningen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Dick Veldhuis (Dr.)
LEIBNIZ-INSTITUT DSMZ-DEUTSCHE SAMMLUNG VON MIKROORGANISMEN UND ZELLKULTUREN GMBH
Germany
EU contribution
€ 227 568,88
Address
Inhoffenstrasse 7B
38124 Braunschweig
Activity type
Research Organisations
Administrative Contact
Birgit Gerstel (Dr.)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland
EU contribution
€ 250 314,46
Address
Western Road
T12 YN60 Cork
Activity type
Higher or Secondary Education Establishments
Administrative Contact
David O'connell (Dr.)
PHARMAMAR, S.A.
Spain
EU contribution
€ 200 683,78
Address
Avda. De Los Reyes , Poligono Industrial La Mina 1
28770 Colmenar Viejo (Madrid)
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Simon Munt (Dr.)