Objective "Plant natural products have been utilised by human civilisation for millennia, providing vital medicines and essential dietary components. More recently bioactive compounds from plant sources have been used in cosmetics, as health supplements and are important components of feedstuffs. Despite significant investments new activities and new sustainable biosources are required to alleviate our reliance on chemical synthesis. In the DISCO project we aim to address these issues and create a framework that can act as a generic pipeline capable of taking discovery through application and validation, to translation and industrial valorisation. Key aspects of the project will be concerned with (i) translating discovery into industrial feasibility and/or commercialisation, (ii) transfer our knowledge gained optimising isoprenoid/terpenoid production to other important terpenoids and different classes of natural products, (iii) maintaining and incorporating the very latest technologies into both the discovery and translational pipelines and (iv) develop “green factories” with integrated biorefining pipelines to reduce or eliminate chemical refining and thus environmental impact. The bioactive molecules and their biochemical pathways targeted include, carotenoids (including apo-carotenoids), terpenoids and tropane alkaloid. For example; ketocarotenoids which are used as colorants in feedstuffs especially aquaculture; colourless carotenes such as phytoene and phytofluene, which are important bioactive ingredients of cosmetics; apo-carotenoids from saffron which are colorants and potent bioactives; the terpenoid solanesol which is used in the production of Coenzyme Q10 and the alkaloid scopolamine which is used as analgesic. The project will have real-life impacts reducing environmental impact, provide new material to benefit human activities and stimulate economic development." Fields of science agricultural sciencesagriculture, forestry, and fisheriesfisheriesengineering and technologymaterials engineeringcolors Programme(s) FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology Topic(s) KBBE.2013.3.1-01 - Plant High Value Products - from discovery to final product Call for proposal FP7-KBBE-2013-7-single-stage See other projects for this call Funding Scheme CP-TP - Collaborative Project targeted to a special group (such as SMEs) Coordinator ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE Address Egham hill university of london TW20 0EX Egham United Kingdom See on map Region South East (England) Surrey, East and West Sussex West Surrey Activity type Higher or Secondary Education Establishments Administrative Contact Paul Fraser (Dr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 977 036,00 Participants (14) Sort alphabetically Sort by EU Contribution Expand all Collapse all MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV Germany EU contribution € 659 600,00 Address Hofgartenstrasse 8 80539 Munchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Research Organisations Administrative Contact Nicole Portée (Ms.) Links Contact the organisation Opens in new window Website Opens in new window THE HEBREW UNIVERSITY OF JERUSALEM Israel EU contribution € 349 136,00 Address Edmond j safra campus givat ram 91904 Jerusalem See on map Activity type Higher or Secondary Education Establishments Administrative Contact Jane Turner (Ms.) Links Contact the organisation Opens in new window Website Opens in new window AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE Italy EU contribution € 437 845,00 Address Lungotevere grande ammiraglio thaon di revel 76 00196 Roma See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Administrative Contact Giovanni Giuliano (Prof.) Links Contact the organisation Opens in new window Website Opens in new window FUNDACION FRAUNHOFER CHILE RESEARCH Chile EU contribution € 453 213,00 Address Avenida mariano sanchez fontecilla 310 7550296 Santiago de chile See on map Activity type Research Organisations Administrative Contact Vera Wodarz Links Contact the organisation Opens in new window Website Opens in new window THE JAMES HUTTON INSTITUTE United Kingdom EU contribution € 532 153,00 Address Errol road invergowrie DD2 5DA Dundee See on map Region Scotland Eastern Scotland Perth & Kinross and Stirling Activity type Research Organisations Administrative Contact Karen Robb (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window TECHNISCHE UNIVERSITAT DORTMUND Germany EU contribution € 569 400,00 Address August schmidt strasse 4 44227 Dortmund See on map Region Nordrhein-Westfalen Arnsberg Dortmund, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Oliver Kayser (Prof.) Links Contact the organisation Opens in new window Website Opens in new window THE AGRICULTURAL RESEARCH ORGANISATION OF ISRAEL - THE VOLCANI CENTRE Israel EU contribution € 310 824,00 Address Derech hamcabim 68 50250 Bet dagan See on map Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Ruth Lerer (Ms.) Links Contact the organisation Opens in new window Website Opens in new window PROPLANTA SRL Romania EU contribution € 300 320,00 Address Str ioan budai deleanu 28 400474 Cluj napoca See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Carmen Socaciu (Prof.) Links Contact the organisation Opens in new window Website Opens in new window FERMENTED PRODUCT PARTNER Belgium EU contribution € 366 080,00 Address Rue herman meganck 21 5032 Gembloux-les isnes See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Véronique Vlieghe (Mrs.) Links Contact the organisation Opens in new window EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH Germany EU contribution € 503 950,00 Address Heinrich-hertz-allee 1 66386 St ingbert See on map Region Saarland Saarland Saarpfalz-Kreis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Verena Peuser (Dr.) Links Contact the organisation Opens in new window Website Opens in new window ISRAELI BIOTECHNOLOGY RESEARCH LTD Israel EU contribution € 381 600,00 Address Pekeris 4 lev hatamar building 76702 Rehovot See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Fabien Havas (Dr.) Links Contact the organisation Opens in new window Website Opens in new window SB DRUG DISCOVERY LIMITED United Kingdom EU contribution € 316 050,00 Address Telford pavilion block h todd campus G20 0XA Glasgow See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Ian Mcphee (Dr.) Links Contact the organisation Opens in new window Website Opens in new window IGA TECHNOLOGY SERVICES SRL Italy EU contribution € 280 640,00 Address Via linussio 51 33100 Udine See on map Region Nord-Est Friuli-Venezia Giulia Udine Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Federica Cattonaro (Dr.) Links Contact the organisation Opens in new window Website Opens in new window BOEHRINGER INGELHEIM PHARMA GMBH &CO KG Germany EU contribution € 48 000,00 Address Binger strasse 173 55218 Ingelheim See on map Region Baden-Württemberg Stuttgart Stuttgart, Stadtkreis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Hansjörg Hagels (Dr.) Links Contact the organisation Opens in new window Website Opens in new window