Skip to main content

Synthetic Cellular Signaling Circuits

Objective

Cellular signaling systems are crucially important for a broad range of critical health and disease areas and high value industrial applications. Signaling systems are the target for more than half of the medicines marketed by the pharmaceutical industry, and form the main R&D area for the nutrition, flavour and fragrance industries. SynSignal is a multidisciplinary high-tech consortium working in synthetic biology's area of greatest untapped potential, delivering a synthetic biology toolbox and finished products custom designed for major present and future industrial applications of cellular signaling. Based on the leading expertise and innovative drive of the partners, SynSignal will address this urgent and imposing bottleneck, by providing new and sophisticated synthetic biology tools and technologies to overcome the challenges currently facing signaling-based product development. Putting in place the technological innovations, toolboxes, and application-focused materials created during SynSignal will have a dramatic impact on the accessibility of drug discovery technologies, particularly for cancer and diabetes, and for enabling technologies to create the next generation of flavours, fragrances, and nutritional ingredients. Our innovations will provide immediate benefits to the health and well-being of Europe’s citizens and to the competitiveness of key European industries alike, and catalyze their transition towards sustainable production principles. In addition, all partners in SynSignal themselves will draw great benefit from the activities proposed. Private sector partners will considerably enhance their discovery and technology platforms, thereby increasing their efficiency, output and valuation. Academic partners in SynSignal will decisively advance fundamental life science research in their laboratories and in the larger scientific community by creating enabling tools to tackle biological questions of unprecedented complexity in cellular signaling.

Call for proposal

FP7-KBBE-2013-7-single-stage
See other projects for this call

Coordinator

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Address
Batiment Ce 3316 Station 1
1015 Lausanne
Switzerland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 183 530,11
Administrative Contact
Horst Vogel (Prof.)

Participants (9)

EUROPEAN MOLECULAR BIOLOGY LABORATORY

Participation ended

Germany
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
Administrative Contact
Sonja Noss (Ms.)
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Ireland
EU contribution
€ 738 232,70
Address
Belfield
4 Dublin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Donal Doolan (Mr.)
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 915 967,45
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Therese Kindåker (Ms.)
DEUTSCHES INSTITUT FUER ERNAEHRUNGSFORSCHUNG POTSDAM REHBRUECKE
Germany
EU contribution
€ 880 237,45
Address
Arthur-scheunert-allee 114-116
14558 Nuthetal
Activity type
Research Organisations
Administrative Contact
Judith Schaefer (Dr.)
FUNDACIO CENTRE DE REGULACIO GENOMICA
Spain
EU contribution
€ 727 104,40
Address
Carrer Doctor Aiguader 88
08003 Barcelona
Activity type
Research Organisations
Administrative Contact
Stefan Pönisch (Mr.)
BIO-XTAL SARL
France
EU contribution
€ 722 000
Address
Rue Thomas Edison 2
67450 Mundolsheim
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Etienne L'hermite (Mr.)
GBIOTECH SARL
Switzerland
EU contribution
€ 1 163 441,25
Address
Chemin Des Aulx 14
1228 Plan Les Ouates
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Daniel Fitzgerald (Dr.)
EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH
Germany
EU contribution
€ 562 569,64
Address
Heinrich-hertz-allee 1
66386 St Ingbert
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Vera Schneider (Dr.)
UNIVERSITY OF BRISTOL
United Kingdom
EU contribution
€ 386 120
Address
Beacon House Queens Road
BS8 1QU Bristol
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Sarah Everett-Cox (Mrs.)