Final Report Summary - NEUROVISION (The organisation of functional microcircuits in visual cortex)
To address this question, the research in my laboratory has focused on uncovering the fundamental principles of neural circuit organization, how this organization relates to the computations that support visual function. Our approach was to (i) record activity in identified neurons in large ensembles to uncover the computations taking place during visual processing and visually-guided behaviours, (ii) deduce how these computations arise from the neural hardware: from the synaptic interactions between identified cell types that differ in the patterns of input and output connectivity. We hope that this work will provide a basis for understanding how computation within neocortex is altered in diseases such as schizophrenia or autism spectrum disorders.