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Cell Metabolomics on A Chip By Integrated High-Resolution NMR Spectroscopy

Objective

uF-NMR aims at the development of microfluidic devices that allow the culture and manipulation of populations of live cells while characterising their metabolome in situ through NMR spectroscopy. The basic paradigm is the direct interrogation of sample volumes on the chip. This is achieved through integrating micro-fabricated radio frequency resonators into the microfluidic device. Rather than extracting aliquots for analysis, the entire chip is inserted into a specially designed NMR probe for the measurement. This work will combine the power of emerging microfluidic lab-on-a-chip techniques with the specificity, versatility, and resolution of NMR spectroscopy.

Field of science

  • /natural sciences/chemical sciences/analytical chemistry/spectroscopy
  • /engineering and technology/electrical engineering, electronic engineering, information engineering/information engineering/telecommunications/radio technology/radio frequency

Call for proposal

FP7-PEOPLE-2013-CIG
See other projects for this call

Funding Scheme

MC-CIG - Support for training and career development of researcher (CIG)

Coordinator

UNIVERSITY OF SOUTHAMPTON
Address
Highfield
SO17 1BJ Southampton
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 100 000
Administrative Contact
Yan Qiao (Ms.)