Objective
"Proteins are highly dynamic machines, perfectly engineered by nature to fulfil their dedicated function like e.g. catalysis of chemical reactions or signalling processes. Crystallography and ultrafast spectroscopy techniques gave fundamental insights to develop a time-resolved picture of biological function. However experimental tools to study ultrafast protein dynamics with atomic and ultrafast time resolution in the same experiment to fully access and describe the structure-function correlation of biochemical processes have been lacking so far. The ambitious goal of the proposed project is to explore sample preparation strategies for the test systems Bacteriorhodopsin and Myoglobin/Hemoglobin to extend the new technology ""Femtosecond electron diffraction"" (FED) to studies of proteins. FED is a method complementary to ultrafast studies using new X-ray free electron laser sources. The main challenge for this study is sufficient sample preparation and development. For this the group of Oliver P. Ernst at University of Toronto, a world-known structural biologist specialized in rhodopsin research, acts as outgoing host. In the group of R. J. Dwayne Miller, acting as host, at Max-Planck-Institute for Structure and Dynamics of Matter, Hamburg, the femtosecond electron diffraction experiments will be carried out, grounded on their expertise as the world-leading group in developing ultrabright electron sources on par with the European XFEL and inventors of the FED technology. The researcher Henrike M. Müller-Werkmeister is the perfect candidate for this extremely interdisciplinary project, as biochemist by training and experienced in measurements of ultrafast biomolecular dynamics using multidimensional laser spectroscopy."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences earth and related environmental sciences geology mineralogy crystallography
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences chemical sciences
- natural sciences physical sciences optics laser physics
- natural sciences physical sciences optics spectroscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IOF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
80539 MUNCHEN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.