Objective
"MICartRegen is a multidisciplinary and highly innovative project aimed at designing and producing a novel multi-biofunctional, cell-free prototype orthopaedic implant able to induce, stimulate and sustain self-repair of injured cartilage tissue. This implant would be used to promote the in-situ regeneration of functional articular cartilage in lesions caused by trauma and early stage osteoarthritis. The proposed implant is novel, cell-free and differs in its mode of action from other devices on the market.
In brief, the implant will contain a) Bioactive molecules to recruit and retain ""repair cells"" (mesenchymal stem cells) from the joint fluid or released by the orthopaedic surgeon by subchondral drilling; b) Bioactive factors to promote maturation of the recruited stem cells into cartilage cells (chondrocytes) to produce the required extracellular matrix components. The technologies used to fabricate the prototype implant are adaptable, therefore custom fabrication of sophisticated bioactive scaffolds for different biomaterials containing various bioactive factors would be possible
The success of the project relies on the strong background in biomaterials science, largely in bio-functionalisation and genetic activation of materials, of the candidate, combined with complimentary skills and infrastructure of the host.
MICartRegen will also give the candidate an opportunity to be trained in new methods on biological evolution of biomaterials, and transferable skills that will greatly boost her career. Furthermore, it will help her to become an independent and experienced researcher able to plan and manage her research, disseminate the results, up to industrial exploitation, through participation in courses and cooperation with experienced scientists."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences medical biotechnology cells technologies stem cells
- engineering and technology industrial biotechnology biomaterials
- medical and health sciences medical biotechnology implants
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
S10 2TN SHEFFIELD
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.