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Antibody-responses to Helicobacter pylori and tumour proteins as biomarkers for early gastric cancer

Objective

This proposal concerns an outgoing fellowship for Samuel Lundin (SL), PhD, Dept. of Microbiology and Immunology, University of Gothenburg. To further develop and substantially boost his scientific career, SL will for two years visit the laboratory of Professor Barry Marshall, University of Western Australia, Perth, Australia.
SL has a good track record in science, but lacks crucial skills in bioinformatics and H. pylori genomics. The fellowship at the Marshall group will alleviate this and thereby allow SL to perform research at the top international level.

Gastric cancer is the second most common cause of cancer-related death worldwide, and is particularly prevalent in East Asia, Eastern Europe and Central and South America. This cancer type is caused by Helicobacter pylori, a bacterium that was discovered by the outgoing host Prof. Marshall.

The proposed research project aims to identify antibody signatures to Helicobacter pylori infection and tumour proteins as serological biomarkers for early gastric cancer. Such biomarkers would allow screening and early detection of gastric cancer, which most likely would lead to increased survival.

Therefore, this project has the potential to lead to a reduced mortality of gastric cancer, and it will also add significantly to European research and to the biotech industry.

Call for proposal

FP7-PEOPLE-2013-IOF
See other projects for this call

Coordinator

GOETEBORGS UNIVERSITET
Address
Vasaparken
405 30 Goeteborg
Sweden
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 390 265
Administrative Contact
Ellen Rydberg (Dr.)