Strengthening Animal Production and Health through the Immune Response

Informations projet

SAPHIR

N° de convention de subvention: 633184

DOI 10.3030/633184

Projet clôturé

Date de signature de la CE 18 Février 2015

Date de début 1 Mars 2015

Date de fin 28 Février 2019

Financé au titre de

• SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy

Coût total € 10 549 121,50

Contribution de l’UE € 8 999 996,25

Coordonné par

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
France

Livrables

Documents, reports (20)

Responsiveness of porcine DC and B cells, and chicken DC, to individual and combined TLR ligands

Responsiveness of porcine DC and B cells and chicken DC to individual and combined TLR ligands report

Collected data for analysis of the factors involved in vaccine perception
SAPHIR project management guidelines
Identification of age categories of cattle that need to be targeted for vaccination in order to prevent virus circulation

Identification of age categories of cattle that need to be targeted for vaccination in order to prevent virus circulation (report).

Age-related innate responses to different TLR ligands in pig in vitro

Agerelated innate responses to different TLR ligands in pig in vitro report

Age-related innate responses to different adjuvants in cattle in vitro

Age-related innate responses to different adjuvants in cattle in vitro (report).

Outreach, training and dissemination plan

Outreach training and dissemination plan

Identification of immune correlates of protection that can be used to estimate the level of protection against infection by BRSV in the field

Identification of immune correlates of protection that can be used to estimate the level of protection against infection by BRSV in the field report

Effect of TLR-L on vaccine-induced immune responses and their protective value

Effect of TLR-L on vaccine-induced immune responses and their protective value (report)

Production and characterisation of the pre-fusion form of the BRSV F protein

Production and characterisation of the prefusion form of the BRSV F protein report

Protection against PRRSV by transfer of T and enriched CD8+ T cells

Report on protection against PRRSV by transfer of T and enriched CD8+ T cells

Conceptual framework of the factors involved in livestock producers’ attitude towards the intervention strategies against SAPHIR diseases, including vaccination

Conceptual framework of the factors involved in livestock producers attitude towards the intervention strategies against SAPHIR diseases including vaccination framework on farmers perception of interventions against SAPHIR diseases

Knowledge on the role of antibodies in protection

Report on knowledge on the role of antibodies in protection

Identification of CD8+ T cell PRRSV protein targets

Report on the identification of CD8 T cell PRRSV protein targets

Chicken DC and macrophage gene expression profiling in response to TLR ligands

Chicken DC and macrophage gene expression profiling in response to TLR ligands report

Optimized formulation for co-delivery of TLR-L and antigen in pigs and chickens

Optimized formulation for codelivery of TLRL and antigen in pigs and chickens report

Identification of the key factors that influence livestock producers’ behaviours towards vaccination and control of SAPHIR diseases, including information relevant to economic modelling for WP1

Identification of the key factors of farmers behaviours towards vaccination and control of SAPHIR diseases including information relevant to economic modelling for WP1

Economic analysis the SAPHIR diseases and their existing control measures

Framework for economic impact assessment of Saphir diseases and pathogens

Production losses caused by SAPHIR diseases and pathogens

Report on the estimation of production losses caused by SAPHIR diseases and pathogens

Farm-level impacts of SAPHIR diseases and pathogens

Report on Farmlevel impacts of SAPHIR diseases and pathogens

Other (5)

Workshop N°1 with stakeholders

Workshop N1 with stakeholders

Identification of the candidate risk factors of existing and new vaccines against the SAPHIR pathogens (wiki-website)
Launching of the Global Alliance for Veterinary Vaccinolog

Launching of the Global Alliance for Veterinary Vaccinology

Biorepository of biological samples and construction of a database data management

Biorepository of biological samples and construction of a database data management database

Workshop N°2 with stakeholders

Workshop N°2 with stakeholders.

Websites, patent fillings, videos etc. (2)

Project website on-line

Project website online

Integrated animal health management website on-line

Integrated animal health management website online

Publications

Peer reviewed articles (27)

Porcine B Cell Subset Responses to Toll-like Receptor Ligands

Auteurs: Roman Othmar Braun, Sylvie Python, Artur Summerfield
Publié dans: Frontiers in Immunology, Numéro 8, 2017, Page(s) 1-14, ISSN 1664-3224
Éditeur: Frontiers
DOI: 10.3389/fimmu.2017.01044

Proteome analysis of bronchoalveolar lavage from calves infected with bovine respiratory syncytial virus—Insights in pathogenesis and perspectives for new treatments

Auteurs: Sara Hägglund, Krister Blodörn, Katarina Näslund, Karin Vargmar, Sara Bergström Lind, Jia Mi, Mariluz Araínga, Sabine Riffault, Geraldine Taylor, John Pringle, Jean François Valarcher
Publié dans: PLOS ONE, Numéro 12/10, 2017, Page(s) e0186594, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0186594

Linking disease epidemiology and livestock productivity: The case of bovine respiratory disease in France

Auteurs: Alexis Delabouglise, Andrew James, Jean-François Valarcher, Sara Hagglünd, Didier Raboisson, Jonathan Rushton
Publié dans: PLOS ONE, Numéro 12/12, 2017, Page(s) e0189090, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0189090

Recombinant anticoccidial vaccines - a cup half full?

Auteurs: Damer P. Blake, Iván Pastor-Fernández, Matthew J. Nolan, Fiona M. Tomley
Publié dans: Infection, Genetics and Evolution, Numéro 55, 2017, Page(s) 358-365, ISSN 1567-1348
Éditeur: Elsevier BV
DOI: 10.1016/j.meegid.2017.10.009

Vaccines as alternatives to antibiotics for food producing animals. Part 1: challenges and needs

Auteurs: Karin Hoelzer, Lisa Bielke, Damer P. Blake, Eric Cox, Simon M. Cutting, Bert Devriendt, Elisabeth Erlacher-Vindel, Evy Goossens, Kemal Karaca, Stephane Lemiere, Martin Metzner, Margot Raicek, Miquel Collell Suriñach, Nora M. Wong, Cyril Gay, Filip Van Immerseel
Publié dans: Veterinary Research, Numéro 49/1, 2018, Page(s) 64, ISSN 1297-9716
Éditeur: Springer Nature
DOI: 10.1186/s13567-018-0560-8

Label-Free Quantitative Proteomic Analysis of Differentially Expressed Membrane Proteins of Pulmonary Alveolar Macrophages Infected with Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus and Its Attenuated Strain

Auteurs: Zehui Qu, Fei Gao, Liwei Li, Yujiao Zhang, Yifeng Jiang, Lingxue Yu, Yanjun Zhou, Hao Zheng, Wu Tong, Guoxin Li, Guangzhi Tong
Publié dans: PROTEOMICS, Numéro 17/23-24, 2017, Page(s) 1700101, ISSN 1615-9853
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/pmic.201700101

Neonatal porcine blood derived dendritic cell subsets show activation after TLR2 or TLR9 stimulation

Auteurs: Sandra Vreman, Gael Auray, Huub F.J. Savelkoul, Annemarie Rebel, Artur Summerfield, Norbert Stockhofe-Zurwieden
Publié dans: Developmental & Comparative Immunology, Numéro 84, 2018, Page(s) 361-370, ISSN 0145-305X
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.dci.2018.03.012

Recombinant porcine reproductive and respiratory syndrome virus expressing luciferase genes provide a new indication of viral propagation in both permissive and target cells

Auteurs: Fei Gao, Zehui Qu, Liwei Li, Lingxue Yu, Yifeng Jiang, Yanjun Zhou, Shen Yang, Hao Zheng, Qinfeng Huang, Wu Tong, Guangzhi Tong
Publié dans: Research in Veterinary Science, Numéro 107, 2016, Page(s) 132-140, ISSN 0034-5288
Éditeur: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.rvsc.2016.05.014

Genetic variability and limited clonality of Mycoplasma hyorhinis in pig herds

Auteurs: Bettina Trüeb, Elena Catelli, Adrian Luehrs, Heiko Nathues, Peter Kuhnert
Publié dans: Veterinary Microbiology, Numéro 191, 2016, Page(s) 9-14, ISSN 0378-1135
Éditeur: Elsevier BV
DOI: 10.1016/j.vetmic.2016.05.015

Using a One Health approach to assess the impact of parasitic disease in livestock: how does it add value?

Auteurs: JONATHAN RUSHTON, MIEGHAN BRUCE
Publié dans: Parasitology, 2016, Page(s) 1-11, ISSN 0031-1820
Éditeur: Cambridge University Press
DOI: 10.1017/S0031182016000196

Development of cross-protective Eimeria-vectored vaccines based on apical membrane antigens

Auteurs: Iván Pastor-Fernández, Sungwon Kim, Karen Billington, Janene Bumstead, Virginia Marugán-Hernández, Tatiana Küster, David J.P. Ferguson, Lonneke Vervelde, Damer P. Blake, Fiona M. Tomley
Publié dans: International Journal for Parasitology, Numéro 48/7, 2018, Page(s) 505-518, ISSN 0020-7519
Éditeur: Elsevier BV
DOI: 10.1016/j.ijpara.2018.01.003

Porcine Reproductive and Respiratory Syndrome Virus Type 1.3 Lena Triggers Conventional Dendritic Cells 1 Activation and T Helper 1 Immune Response Without Infecting Dendritic Cells

Auteurs: Elise Bordet, Fany Blanc, Mathieu Tiret, Elisa Crisci, Edwige Bouguyon, Patricia Renson, Pauline Maisonnasse, Mickael Bourge, Jean-Jacques Leplat, Elisabetta Giuffra, Luc Jouneau, Isabelle Schwartz-Cornil, Olivier Bourry, Nicolas Bertho
Publié dans: Frontiers in Immunology, Numéro 9, 2018, ISSN 1664-3224
Éditeur: Frontiers
DOI: 10.3389/fimmu.2018.02299

Porcine Alveolar Macrophage-like cells are pro-inflammatory Pulmonary Intravascular Macrophages that produce large titers of Porcine Reproductive and Respiratory Syndrome Virus

Auteurs: Elise Bordet, Pauline Maisonnasse, Patricia Renson, Edwige Bouguyon, Elisa Crisci, Mathieu Tiret, Delphyne Descamps, Cindy Bernelin-Cottet, Céline Urien, François Lefèvre, Luc Jouneau, Olivier Bourry, Jean-Jacques Leplat, Isabelle Schwartz-Cornil, Nicolas Bertho
Publié dans: Scientific Reports, Numéro 8/1, 2018, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-018-28234-y

Synergistic effect of co-stimulation of membrane and endosomal TLRs on chicken innate immune responses

Auteurs: Sungwon Kim, Pete Kaiser, Dominika Borowska, Lonneke Vervelde
Publié dans: Veterinary Immunology and Immunopathology, Numéro 199, 2018, Page(s) 15-21, ISSN 0165-2427
Éditeur: Elsevier BV
DOI: 10.1016/j.vetimm.2018.03.005

How to prevent viremia rebound? Evidence from a PRRSv data-supported model of immune response

Auteurs: Natacha Go, Suzanne Touzeau, Zeenath Islam, Catherine Belloc, Andrea Doeschl-Wilson
Publié dans: BMC Systems Biology, Numéro 13/1, 2019, ISSN 1752-0509
Éditeur: BioMed Central
DOI: 10.1186/s12918-018-0666-7

Comparison of six commercial ELISAs for the detection of antibodies against porcine reproductive and respiratory syndrome virus (PRRSV) in field serum samples

Auteurs: Kinga Biernacka, Katarzyna Podgórska, Anna Tyszka, Tomasz Stadejek
Publié dans: Research in Veterinary Science, Numéro 121, 2018, Page(s) 40-45, ISSN 0034-5288
Éditeur: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.rvsc.2018.10.005

Galectin-3 inhibits replication of porcine reproductive and respiratory syndrome virus by interacting with viral Nsp12 in vitro

Auteurs: Liwei Li, Yanjun Zhou, Yifeng Jiang, Fei Gao, Tongling Shan, Kuan Zhao, Yujiao Zhang, Lin Li, Guangzhi Tong
Publié dans: Virus Research, Numéro 253, 2018, Page(s) 87-91, ISSN 0168-1702
Éditeur: Elsevier BV
DOI: 10.1016/j.virusres.2018.06.006

Porcine reproductive and respiratory syndrome virus expressing E2 of classical swine fever virus protects pigs from a lethal challenge of highly-pathogenic PRRSV and CSFV

Auteurs: Fei Gao, Yifeng Jiang, Guoxin Li, Yanjun Zhou, Lingxue Yu, Liwei Li, Wu Tong, Hao Zheng, Yujiao Zhang, Hai Yu, Tongling Shan, Shen Yang, Huan Liu, Kuan Zhao, Guangzhi Tong
Publié dans: Vaccine, Numéro 36/23, 2018, Page(s) 3269-3277, ISSN 0264-410X
Éditeur: Elsevier BV
DOI: 10.1016/j.vaccine.2018.04.079

Development of Monoclonal Antibodies Specifically Recognizing the Nonstructural Protein 12 of Type 2 Porcine Reproductive and Respiratory Syndrome Virus

Auteurs: Liwei Li, Fei Gao, Yifeng Jiang, Wu Tong, Hao Zheng, Tongling Shan, Ning Kong, Hai Yu, Deqiang Yang, Kuan Zhao, Yujiao Zhang, Guangzhi Tong
Publié dans: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, Numéro 37/2, 2018, Page(s) 73-77, ISSN 2167-9436
Éditeur: Mary Ann Liebert Inc.
DOI: 10.1089/mab.2017.0060

MOV10 inhibits replication of porcine reproductive and respiratory syndrome virus by retaining viral nucleocapsid protein in the cytoplasm of Marc-145 cells

Auteurs: Kuan Zhao, Li-Wei Li, Yu-Jiao Zhang, Yi-Feng Jiang, Fei Gao, Guo-Xin Li, Ling-Xue Yu, Wen-Ying Zhao, Tong-Ling Shan, Yan-Jun Zhou, Guang-Zhi Tong
Publié dans: Biochemical and Biophysical Research Communications, Numéro 504/1, 2018, Page(s) 157-163, ISSN 0006-291X
Éditeur: Academic Press
DOI: 10.1016/j.bbrc.2018.08.148

Utilizing host endogenous microRNAs to negatively regulate the replication of porcine reproductive and respiratory syndrome virus in MARC-145 cells

Auteurs: Liwei Li, Fei Gao, Hao Zheng, Yifeng Jiang, Wu Tong, Yanjun Zhou, Guangzhi Tong
Publié dans: PLOS ONE, Numéro 13/7, 2018, Page(s) e0200029, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0200029

A DNA Prime Immuno-Potentiates a Modified Live Vaccine against the Porcine Reproductive and Respiratory Syndrome Virus but Does Not Improve Heterologous Protection

Auteurs: Cindy Bernelin-Cottet, Céline Urien, Maxence Fretaud, Christelle Langevin, Ivan Trus, Luc Jouneau, Fany Blanc, Jean-Jacques Leplat, Céline Barc, Olivier Boulesteix, Mickaël Riou, Marilyn Dysart, Sophie Mahé, Elisabeth Studsrub, Hans Nauwynck, Nicolas Bertho, Olivier Bourry, Isabelle Schwartz-Cornil
Publié dans: Viruses, Numéro 11/6, 2019, Page(s) 576, ISSN 1999-4915
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11060576

Systems Immunology Characterization of Novel Vaccine Formulations for Mycoplasma hyopneumoniae Bacterins

Auteurs: Anneleen M. F. Matthijs, Gaël Auray, Virginie Jakob, Obdulio García-Nicolás, Roman O. Braun, Irene Keller, Rémy Bruggman, Bert Devriendt, Filip Boyen, Carlos A. Guzman, Annelies Michiels, Freddy Haesebrouck, Nicolas Collin, Christophe Barnier-Quer, Dominiek Maes, Artur Summerfield
Publié dans: Frontiers in Immunology, Numéro 10, 2019, ISSN 1664-3224
Éditeur: Frontiers
DOI: 10.3389/fimmu.2019.01087

Electroporation of a nanoparticle-associated DNA vaccine induces higher inflammation and immunity compared to its delivery with microneedle patches in pigs

Auteurs: Cindy Bernelin-Cottet, Céline Urien, Joanne McCaffrey, Damien Collins, Agnese Donadei, Dennis McDaid, Virginie Jakob, Christophe Barnier-Quer, Nicolas Collin, Edwige Bouguyon, Elise Bordet, Céline Barc, Olivier Boulesteix, Jean-Jacques Leplat, Fany Blanc, Vanessa Contreras, Nicolas Bertho, Anne C. Moore, Isabelle Schwartz-Cornil
Publié dans: Journal of Controlled Release, Numéro 308, 2019, Page(s) 14-28, ISSN 0168-3659
Éditeur: Elsevier BV
DOI: 10.1016/j.jconrel.2019.06.041

Predicting vaccine effectiveness in livestock populations: A theoretical framework applied to PRRS virus infections in pigs

Auteurs: Vasiliki Bitsouni, Samantha Lycett, Tanja Opriessnig, Andrea Doeschl-Wilson
Publié dans: PLOS ONE, Numéro 14/8, 2019, Page(s) e0220738, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0220738

Tn-sequencing of Mycoplasma hyopneumoniae and Mycoplasma hyorhinis mutant libraries reveals non-essential genes of porcine mycoplasmas differing in pathogenicity

Auteurs: Bettina S. Trueeb, Simona Gerber, Dominiek Maes, Walid H. Gharib, Peter Kuhnert
Publié dans: Veterinary Research, Numéro 50/1, 2019, Page(s) 55, ISSN 1297-9716
Éditeur: Springer Nature
DOI: 10.1186/s13567-019-0674-7

A DNA-Modified Live Vaccine Prime–Boost Strategy Broadens the T-Cell Response and Enhances the Antibody Response against the Porcine Reproductive and Respiratory Syndrome Virus

Auteurs: Cindy Bernelin-Cottet, Céline Urien, Elisabeth Stubsrud, Virginie Jakob, Edwige Bouguyon, Elise Bordet, Céline Barc, Olivier Boulesteix, Vanessa Contreras, Christophe Barnier-Quer, Nicolas Collin, Ivan Trus, Hans Nauwynck, Nicolas Bertho, Isabelle Schwartz-Cornil
Publié dans: Viruses, Numéro 11/6, 2019, Page(s) 551, ISSN 1999-4915
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11060551

Conference proceedings (27)

"“Exploring the thinking of ‘Good Farming’ in pig production industries between Europe and China: a sociological analysis of farmers’ attitudes towards animal diseases and vaccination practices"""

Auteurs: Chan, R. and Enticott, G.
Publié dans: n/a, Numéro 2017, 2017
Éditeur: -

Dissolving microneedle patches adjuvanted with different Toll like receptor agonists in pigs: local immune response by macroscopic and histologic evaluation

Auteurs: S. Vremen, J. McCaffrey, N. Stochofe, A.C, Moore
Publié dans: Skin Vaccination Summit, Numéro may 2017, 2017, Page(s) 36
Éditeur: -

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Auteurs: Sabine Riffault
Publié dans: Numéro 12 December 2017, 2017
Éditeur: 7e Workshop CoReVac / I-REIVAC, Vaccination in the extreme ages of life

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Auteurs: Sabine Riffault
Publié dans: -, Numéro 26 - 27 October 2017, 2017
Éditeur: Colloque Département Sciences de la Vie de l’Université Paris-Saclay

A one health perspective for vaccine strategies against bronchiolitis

Auteurs: Gabriela Pretre, Stéphane Claverol, Marie-Claude Hygonenq, Christine Citti1 and Eric Baranowski
Publié dans: Abstract Book of the UK Veterinary Vaccinology Network Conference 2017, Numéro 16-17 January 2017, 2017
Éditeur: UK Veterinary Vaccinology Network

Le protéome membranaire de Mycoplasma bovis: à la recherche d’antigènes stables chez un pathogène hypervariable

Auteurs: Gabriela Pretre, Marie-Claude Hygonenq, Stéphane Claverol, Christine Citti and Eric Baranowski
Publié dans: Abstract Book of the 7e Colloque International Francophone de Microbiologie Animale, Numéro 26-27 March 2017, 2017, Page(s) 37
Éditeur: Université de Liège

Deciphering host responses to Eimeria infections for implementing integrated breeding strategies for improved resistance to coccidiosis

Auteurs: Marie-Hélène Pinard-van der Laan
Publié dans: Abstract Book of the 12th International Coccidiosis Conference (ICC-12), Numéro June 26-30, 2017, 2017, Page(s) 41-42
Éditeur: American Society of Parasitologists (ASP)

Genetic individual variability of vaccine responses in pigs

Auteurs: Fany Blanc, Gaëtan Lemonnier, Jean-Jacques Leplat, Edwige Bouguyon, Yvon Billon, Jordi Estellé and Claire Rogel-Gaillard
Publié dans: Abstract Book of the 36th International Society for Animal Genetics (ISAG) Conference, Numéro July 16-21, 2017, 2017, Page(s) 22
Éditeur: Society of Animal Genetics

How to prevent viremia rebound? Evidence from a PRRSv data-supported model of the immune response

Auteurs: N.Go, S. Touzeau, C.Belloc, A. Doeschl-Wilson
Publié dans: ModAH Modelling in Animal Health, Numéro 07.6.2017, 2017
Éditeur: -

New PRRS disease phenotypes as vaccine & genetic improvement targets

Auteurs: A.Doeschl-Wilson
Publié dans: international PRRS symposium 2017, Numéro 2.12.2017, 2017
Éditeur: -

Control measures for bovine respiratory syncytial infection

Auteurs: Hägglund S and Valarcher JF
Publié dans: European Buiatrics Forum, 2015, ISBN 2-9036-23457
Éditeur: Société Francais de Buiatrie

Development of a DNA-loaded dissolving microneedle platform for veterinary vaccination

Auteurs: J. McCaffrey, C. Bernelin, C.Urien, V. Jakob, C. Barnier, N. Bertho, I. Schwartz, D. McDaid, A.Moore
Publié dans: Focused Meeting 2016 – Irish Division: Exploring the Microbe–Immune System Interface, Numéro september 2016, 2016, Page(s) 54
Éditeur: Irish Division: Exploring the Microbe–Immune System Interface

Development of a dissolving microneedle patch for delivery of a veterinary DNA vaccine

Auteurs: J. McCaffrey, C. Bernelin, N. Bertho, I. Schwartz, V. Jakob, C. Barnier, D.McDaid, A.Moore
Publié dans: The 4th International Conference on Microneedles, Numéro may 2016, 2016, Page(s) 18
Éditeur: The 4th International Conference on Microneedles

Vaccination with different Toll-like receptor agonist by dissolving microneedle patches to pigs

Auteurs: Vreman S., McCaffrey J., Rebel A., Moore A., Stockhofe-Zurwieden N.
Publié dans: 2017, Page(s) Poster
Éditeur: Skin vaccination summit

Differential responsiveness of neonatal and adult porcine dendritic cells and monocytes after TLR2 and TLR9 stimulation of PBMCs

Auteurs: Vreman S., Auray G., Savelkoul HFJ, Rebel A., Summerfield A., Stockhofe-Zurwieden N.
Publié dans: 2017, Page(s) Poster
Éditeur: -

Dendritic cells and Porcine Reproductive and Respiratory Syndrome Virus interactions in the lung and their impact on the T helper immune response.

Auteurs: BORDET E, BLANC F, TIRET M, CRISCI E, BOUGUYON E, RENSON P, MAISONNASSE P, BOURGE M, LEPLAT JJ, GIUFFRA E, JOUNEAU L, SCHWARTZ-CORNIL I, BOURRY O, BERTHO N.
Publié dans: "Abstract book of the ""Immunology of Domestic Animals""", 2018
Éditeur: -

Porcine Alveolar Macrophage-like cells are pro-inflammatory Pulmonary Intravascular Macrophages that produce large titers of Porcine Reproductive and Respiratory Syndrome Virus.

Auteurs: BORDET E, MAISONNASSE P, RENSON P, BOUGUYON E, CRISCI E, TIRET M, DESCAMPS D, BERNELIN-COTTET C, URIEN C, LEFÈVRE F, JOUNEAU L, BOURRY O, LEPLAT JJ, SCHWARTZ-CORNIL I, BERTHO N.
Publié dans: "Abstract book of the ""Immunology of Domestic Animals""", 2018
Éditeur: -

Immunogenicity of DNA vaccines delivered by patches and electroporation in pig skin

Auteurs: Bernelin-Cottet C., Urien C., Blanc F., Leplat J.J., McCaffrey J., Collins D., Jakob V., Bordet E., Barc C., Contreras V., Bertho N., McDaid D., Collin N., Barnier-Quer C., Moore A., Schwartz-Cornil I.
Publié dans: Abstract book of European Workshop in Veterinary Immunology, 2018
Éditeur: -

A prime with naked DNA improves the immune responses induced by a modified live vaccine against Porcine Reproductive and Respiratory Syndrome Virus

Auteurs: Bernelin-Cottet C., Urien C., Blanc F., Jakob V., Bordet E., Barc C., Contreras V., Bertho N., Barnier C., Collin N., Studsrub E., Brunsvik Fredriksen A., Trus I., Nauwynck H., and Schwartz-Cornil I.
Publié dans: Abstract book of European congress in Immunonology, 2018
Éditeur: -

Immunogenicity of DNA vaccines delivered by patches and electroporation in pig skin

Auteurs: Bernelin-Cottet C., Urien C., Blanc F., Leplat J.J., McCaffrey J., Collins D., Jakob V., Bordet E., Barc C., Contreras V., Bertho N., McDaid D., Collin N., Barnier-Quer C., Moore A., Schwartz-Cornil I.
Publié dans: Abstract book of European congress in Immunonology, 2018
Éditeur: -

Multidisciplinary approaches to livestock production in SAPHIR

Auteurs: Marie-Hélène Pinard
Publié dans: Abstract book of 69th Annual Meeting of the European Federation of Animal Science (EAAP), 2018
Éditeur: -

What potential of genome-wide integrative approaches to predict vaccine responses?

Auteurs: Blanc F, Maroilley T, Pinard-van der Laan MH, Lemonnier G, Leplat JJ, Bouguyon E, Billon Y, Bidanel JP, Bed’Hom B, Estellé J, Kim S, Vervelde L, Blake D, and Rogel-Gaillard C
Publié dans: Abstract book of 69th Annual Meeting of the European Federation of Animal Science (EAAP), 2018
Éditeur: -

Multi-disciplinary approaches for improving sustainable livestock production: research needs, opportunities and difficulties.

Auteurs: Marie-Hélène Pinard
Publié dans: Abstract book of 69th Annual Meeting of the European Federation of Animal Science (EAAP), 2018
Éditeur: -

Individual genetic variability of vaccine responses in pigs.

Auteurs: Blanc F, Maroilley T, Lemonnier G, Leplat JJ, Bouguyon E, Billon, Bouchez O, Bidanel JP, Bed’Hom 1, Estellé J and Rogel-Gaillard C
Publié dans: "Abstract book of the ""Immunology of Domestic Animals""", 2018
Éditeur: -

Genetic variability of vaccine responses in pigs: application to vaccines against Mycoplasma hyopneumonia and Influenza A virus

Auteurs: Blanc F, Maroilley T, Lemonnier G, Leplat JJ, Bouguyon E, Billon, Bouchez O, Bidanel JP, Bed’Hom B, Estellé J and Rogel-Gaillard C
Publié dans: Abstract book of 6th European Veterinary Immunology Workshop (EVIW), 2018
Éditeur: -

The membrane core proteome of Mycoplasma bovis: A conserved set of antigens within a rapidly changing pathogen

Auteurs: Pretre G, Maillard R, Foucras G, Assié S, Hygonenq MC, Claverol S, Giammarinaro P, Nouvel LX, Guo A, Citti C, Baranowski E.
Publié dans: 22th Congress of the International Organization for Mycoplasmology (IOM2018), 2018
Éditeur: -

Inactivated porcine reproductive and respiratory syndrome virus adjuvanted with single Toll Like receptor 2, 7 and 9 ligands induces low antibody responses and limited protection

Auteurs: Sandra Vreman, Joanne McCaffrey, Ivan Trus, Annemarie Rebel, Hans Nauwynck, Anne Moore, Norbert Stockhofe-Zurwieden
Publié dans: 2018
Éditeur: -

Thesis and dissertations (1)

Développement d’un vaccin à ADN contre le Syndrome Dysgénésique et Respiratoire Porcin (PRRSV)

Auteurs: Cindy Bernelin
Publié dans: 2019
Éditeur: -