ULTRAsensitive PLAsmonic devices for early CAncer Diagnosis

Deliverables

Other (2)

End user workshop organized and feedback collected

Webpage of the project fully operational

At M1 the domain for the website will be blocked and a rudimentary first version of the web-site will be available. The full functionality will be ready at M4.

Documents, reports (1)

Development of the dissemination and communication strategy and project brochure & templates

Publications

Peer reviewed articles (18)

Tearing down the walls: FDA approves next generation sequencing (NGS) assays for actionable cancer genomic aberrations

Author(s): Matteo Allegretti, Alessandra Fabi, Simonetta Buglioni, Aline Martayan, Laura Conti, Edoardo Pescarmona, Gennaro Ciliberto, Patrizio Giacomini
Published in: Journal of Experimental & Clinical Cancer Research, 37/1, 2018, ISSN 1756-9966
Publisher: BMC
DOI: 10.1186/s13046-018-0702-x

A Route to Superior Performance of a Nanoplasmonic Biosensor: Consideration of Both Photonic and Mass Transport Aspects

Author(s): Barbora Špačková, N. Scott Lynn, Jiří Slabý, Hana Šípová, Jiří Homola
Published in: ACS Photonics, 5/3, 2017, Page(s) 1019-1025, ISSN 2330-4022
Publisher: American Chemical Society
DOI: 10.1021/acsphotonics.7b01319

Biosensor platform for parallel surface plasmon-enhanced epifluorescence and surface plasmon resonance detection

Author(s): Agnes T. Reiner, Stefan Fossati, Jakub Dostalek
Published in: Sensors and Actuators B: Chemical, 257, 2018, Page(s) 594-601, ISSN 0925-4005
Publisher: Elsevier BV
DOI: 10.1016/j.snb.2017.10.116

Non-invasive fetal sex diagnosis in plasma of early weeks pregnants using droplet digital PCR

Author(s): Elisabetta D’Aversa, Giulia Breveglieri, Patrizia Pellegatti, Giovanni Guerra, Roberto Gambari, Monica Borgatti
Published in: Molecular Medicine, 24/1, 2018, ISSN 1076-1551
Publisher: North Shore - Long Jewish Research Institute
DOI: 10.1186/s10020-018-0016-7

Peptide Nucleic Acid-Based Biosensors for Cancer Diagnosis

Author(s): Roberta D’Agata, Maria Giuffrida, Giuseppe Spoto
Published in: Molecules, 22/11, 2017, Page(s) 1951, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules22111951

Precision diagnostics of Ewing’s sarcoma by liquid biopsy: circulating EWS-FLI1 fusion transcripts

Author(s): Matteo Allegretti, Beatrice Casini, Chiara Mandoj, Stefania Benini, Laurent Alberti, Mariangela Novello, Elisa Melucci, Laura Conti, Renato Covello, Edoardo Pescarmona, Giuseppe Maria Milano, Alessio Annovazzi, Vincenzo Anelli, Virginia Ferraresi, Roberto Biagini, Patrizio Giacomini
Published in: Therapeutic Advances in Medical Oncology, 10, 2018, Page(s) 175883591877433, ISSN 1758-8359
Publisher: SAGE
DOI: 10.1177/1758835918774337

A Bifunctional Monomer for On-Resin Synthesis of Polyfunctional PNAs and Tailored Induced-Fit Switching Probes

Author(s): Alex Manicardi, Alessandro Bertucci, Andrea Rozzi, Roberto Corradini
Published in: Organic Letters, 18/21, 2016, Page(s) 5452-5455, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.6b02363

Microfluidic Analyte Transport to Nanorods for Photonic and Electrochemical Sensing Applications

Author(s): N. Scott Lynn, Jiří Homola
Published in: Chemistry - A European Journal, 24/46, 2018, Page(s) 12031-12036, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201802757

Surface plasmon modes of nanomesh-on-mirror nanocavities prepared by nanosphere lithography

Author(s): Christian Stelling, Stefan Fossati, Jakub Dostalek, Markus Retsch
Published in: Nanoscale, 10/37, 2018, Page(s) 17983-17989, ISSN 2040-3364
Publisher: Royal Society of Chemistry
DOI: 10.1039/C8NR05499A

Selective Functionalization with PNA of Silicon Nanowires on Silicon Oxide Substrates

Author(s): Janneke Veerbeek, Raymond Steen, Wouter Vijselaar, W. Frederik Rurup, Saša Korom, Andrea Rozzi, Roberto Corradini, Loes Segerink, Jurriaan Huskens
Published in: Langmuir, 34/38, 2018, Page(s) 11395-11404, ISSN 0743-7463
Publisher: American Chemical Society
DOI: 10.1021/acs.langmuir.8b02401

Low-fouling, mixed-charge poly- l -lysine polymers with anionic oligopeptide side-chains

Author(s): Noemi Bellassai, Almudena Marti, Giuseppe Spoto, Jurriaan Huskens
Published in: Journal of Materials Chemistry B, 2018, ISSN 2050-7518
Publisher: Royal Society of Chemistry
DOI: 10.1039/C8TB01619D

Control of Probe Density at DNA Biosensor Surfaces Using Poly( l -lysine) with Appended Reactive Groups

Author(s): Jacopo Movilli, Andrea Rozzi, Roberto Ricciardi, Roberto Corradini, Jurriaan Huskens
Published in: Bioconjugate Chemistry, 2018, ISSN 1043-1802
Publisher: American Chemical Society
DOI: 10.1021/acs.bioconjchem.8b00733

Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review)

Author(s): Alessia Finotti, Matteo Allegretti, Jessica Gasparello, Patrizio Giacomini, Demetrios Spandidos, Giuseppe Spoto, Roberto Gambari
Published in: International Journal of Oncology, 2018, ISSN 1019-6439
Publisher: Demetrios A. Spandidos Ed. & Pub.
DOI: 10.3892/ijo.2018.4516

Streptavidin-coated gold nanoparticles: critical role of oligonucleotides on stability and fractal aggregation

Author(s): Roberta D'Agata, Pasquale Palladino, Giuseppe Spoto
Published in: Beilstein Journal of Nanotechnology, 8, 2017, Page(s) 1-11, ISSN 2190-4286
Publisher: Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
DOI: 10.3762/bjnano.8.1

Focus on PNA Flexibility and RNA Binding using Molecular Dynamics and Metadynamics

Author(s): Massimiliano Donato Verona, Vincenzo Verdolino, Ferruccio Palazzesi, Roberto Corradini
Published in: Scientific Reports, 7, 2017, Page(s) 42799, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/srep42799

DNA Detection by Flow Cytometry using PNA-Modified Metal-Organic Framework Particles

Author(s): Raquel Mejia-Ariza, Jessica Rosselli, Christian Breukers, Alex Manicardi, Leon W. M. M. Terstappen, Roberto Corradini, Jurriaan Huskens
Published in: Chemistry - A European Journal, 23/17, 2017, Page(s) 4180-4186, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201605803

Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology (Review)

Author(s): Roberto Gambari, Eleonora Brognara, Demetrios Spandidos, Enrica Fabbri
Published in: International Journal of Oncology, 49(1), 2016, Page(s) 5-32, ISSN 1019-6439
Publisher: Demetrios A. Spandidos Ed. & Pub.
DOI: 10.3892/ijo.2016.3503

Plasmonically amplified bioassay – Total internal reflection fluorescence vs. epifluorescence geometry

Author(s): Simone Hageneder, Martin Bauch, Jakub Dostalek
Published in: Talanta, 156-157, 2016, Page(s) 225-231, ISSN 0039-9140
Publisher: Elsevier BV
DOI: 10.1016/j.talanta.2016.05.023

Thesis dissertations (6)

Synthesis and Characterization of Novel Photocrosslinkable Poly(2-Oxazoline)-Based Hydrogel Systems for the Application as Biosensor Matrix

Author(s): Christian Petri, Ulrich Jonas
Published in: 2018
Publisher: University of Siegen - Macromolecular Chemistry Department Chemistry - Biology

Advanced PNA-based sensor systems

Author(s): Andrea Rozzi, Roberto Corradini
Published in: 2018
Publisher: University of Parma

Strategie innovative per lo sviluppo di nuovi approcci teranostici: studio del profilo di espressione di microRNA in patologie genetiche e tumorali mediante NGS e ddPCR

Author(s): Papi C, A. Finotti, R. Gambari, J Gasparello
Published in: 2018
Publisher: UNIVERSITA’ DEGLI STUDI DI FERRARA - CORSO DI LAUREA IN CHIMICA E TECNOLOGIA FARMACEUTICHE

Surface Plasmon Resonance Imaging Biosensors for Cancer Diagnosis: Detection of Circulating Tumor DNA

Author(s): Noemi Bellassai, Giuseppe Spoto
Published in: 2018
Publisher: University of Catania

Novel trends in microRNA based theranostics

Author(s): J. Gasparello, A. Finotti, R. Gambari
Published in: 2018
Publisher: UNIVERSITA’ DEGLI STUDI DI FERRARA - PhD Course in Biomedical and Biotechnological Sciences

A liquid biopsy model in mice bearing colorectal carcinoma xenografts: analysis of tumor derived microRNAs

Author(s): G. Donelli, A. Finotti, R. Gambari
Published in: 2016
Publisher: UNIVERSITA’ DEGLI STUDI DI FERRARA - CORSO DI LAUREA IN CHIMICA E TECNOLOGIA

Conference proceedings (1)

A liquid biopsy model: circulating miRNA levels in mice bearing colorectal carcinoma tumor xenografts

Author(s): Finotti, A; Tremante, E; Gasparello, J; Fabbri, E ; Bianchi, N; Allegretti, M ; Giacomini, P; Gambari, R
Published in: International Journal of Molecular Medicine, 2016, Page(s) Vol 38, Supp 1, pag S70, Abstract n° 361
Publisher: D.A. Spandidos

Non-peer reviewed articles (1)

Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA)

Author(s): Jessica Gasparello, Matteo Allegretti, Elisa Tremante, Enrica Fabbri, Carla Azzurra Amoreo, Paolo Romania, Elisa Melucci, Katia Messana, Monica Borgatti, Patrizio Giacomini, Roberto Gambari, Alessia Finotti
Published in: Journal of Experimental & Clinical Cancer Research, 37/1, 2018, ISSN 1756-9966
Publisher: Official journal of the Regina Elena National Cancer Institute, Italy
DOI: 10.1186/s13046-018-0788-1

Book chapters (1)

Responsive polymer networks and brushes for active plasmonics

Author(s): N. G. Quillis, N. Sharma, S. Fossati, W. Knoll, J. Dostalek
Published in: Polymer and Biopolymer Brushes: Fundamentals and Applications in Materials Science and Biotechnology, 2018
Publisher: Omar Azzaroni and Igal Szleifer, John Wiley & Sons, Ltd. 2016

Monographic books (1)

Surface Plasmon Enhanced, Coupled and Controlled Fluorescence

Author(s): Chris D. Geddes
Published in: 2017, ISBN 9781-119325161
Publisher: John Wiley & Sons, Inc.
DOI: 10.1002/9781119325161