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Novel Stromal Cell Therapy for Diabetic Kidney Disease

Deliverables

Dissemination materials

Dissemination materials (brochure, flyer, posters, newsletters)

Website

Website (updated throughout the project)

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Publications

Chronic kidney disease

Author(s): Paola Romagnani, Giuseppe Remuzzi, Richard Glassock, Adeera Levin, Kitty J. Jager, Marcello Tonelli, Ziad Massy, Christoph Wanner, Hans-Joachim Anders
Published in: Nature Reviews Disease Primers, Issue 3, 2017, Page(s) 17088, ISSN 2056-676X
DOI: 10.1038/nrdp.2017.88

Anti-Donor Immune Responses Elicited by Allogeneic Mesenchymal Stem Cells and Their Extracellular Vesicles: Are We Still Learning?

Author(s): Paul Lohan, Oliver Treacy, Matthew D. Griffin, Thomas Ritter, Aideen E. Ryan
Published in: Frontiers in Immunology, Issue 8, 2017, ISSN 1664-3224
DOI: 10.3389/fimmu.2017.01626

Influence of Referral to a Combined Diabetology and Nephrology Clinic on Renal Functional Trends and Metabolic Parameters in Adults With Diabetic Kidney Disease

Author(s): William P. Martin, Tomás P. Griffin, David W. Lappin, Damian G. Griffin, John P. Ferguson, Timothy O'Brien, Matthew D. Griffin
Published in: Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Issue 1/2, 2017, Page(s) 150-160, ISSN 2542-4548
DOI: 10.1016/j.mayocpiqo.2017.07.003

Interspecies Incompatibilities Limit the Immunomodulatory Effect of Human Mesenchymal Stromal Cells in the Rat

Author(s): Paul Lohan, Oliver Treacy, Maurice Morcos, Ellen Donohoe, Yvonne O'donoghue, Aideen E. Ryan, Stephen J. Elliman, Thomas Ritter, Matthew D. Griffin
Published in: STEM CELLS, 2018, ISSN 1066-5099
DOI: 10.1002/stem.2840

Hyperactivation of nuclear receptor coactivators induces PERK-dependent cell death

Author(s): Muhammad Mosaraf Hossain, David Barua, Vahid Arabkari, Nahidul Islam, Ananya Gupta, Sanjeev Gupta
Published in: Oncotarget, Issue 9/14, 2018, ISSN 1949-2553
DOI: 10.18632/oncotarget.24451

Anti-donor antibody induction following intramuscular injections of allogeneic mesenchymal stromal cells

Author(s): Senthilkumar Alagesan, Clara Sanz-Nogués, Xizhe Chen, Michael Creane, Thomas Ritter, Rhodri Ceredig, Timothy O'Brien, Matthew D Griffin
Published in: Immunology and Cell Biology, Issue 96/5, 2018, Page(s) 536-548, ISSN 0818-9641
DOI: 10.1111/imcb.12024

Phenotypic and functional heterogeneity of human intermediate monocytes based on HLA-DR expression

Author(s): Eanna P Connaughton, Serika Naicker, Shirley A Hanley, Stephanie M Slevin, John K Eykelenboom, Noel F Lowndes, Timothy O'Brien, Rhodri Ceredig, Matthew D Griffin, Michael C Dennedy
Published in: Immunology and Cell Biology, 2018, ISSN 0818-9641
DOI: 10.1111/imcb.12032

The Promise of Mesenchymal Stem Cell Therapy for Diabetic Kidney Disease

Author(s): Tomás P. Griffin, William Patrick Martin, Nahidul Islam, Timothy O’Brien, Matthew D. Griffin
Published in: Current Diabetes Reports, Issue 16/5, 2016, ISSN 1534-4827
DOI: 10.1007/s11892-016-0734-6

Clinical Translation of Mesenchymal Stromal Cell Therapies in Nephrology

Author(s): Norberto Perico, Federica Casiraghi, Giuseppe Remuzzi
Published in: Journal of the American Society of Nephrology, Issue 29/2, 2018, Page(s) 362-375, ISSN 1046-6673
DOI: 10.1681/ASN.2017070781

Mesenchymal Stromal Cells for AKI after Cardiac Surgery

Author(s): Norberto Perico, Federica Casiraghi, Giuseppe Remuzzi
Published in: Journal of the American Society of Nephrology, 2018, Page(s) ASN.2017111207, ISSN 1046-6673
DOI: 10.1681/ASN.2017111207

The Immune System in Tissue Environments Regaining Homeostasis after Injury: Is “Inflammation” Always Inflammation?

Author(s): Onkar P. Kulkarni, Julia Lichtnekert, Hans-Joachim Anders, Shrikant R. Mulay
Published in: Mediators of Inflammation, Issue 2016, 2016, Page(s) 1-9, ISSN 0962-9351
DOI: 10.1155/2016/2856213

Chronic kidney disease, health-related quality of life and their associated economic burden among a nationally representative sample of community dwelling adults in England

Author(s): Nga T. Q. Nguyen, Paul Cockwell, Alexander P. Maxwell, Matthew Griffin, Timothy O’Brien, Ciaran O’Neill
Published in: PLOS ONE, Issue 13/11, 2018, Page(s) e0207960, ISSN 1932-6203
DOI: 10.1371/journal.pone.0207960

Defining reference intervals for a serum growth differentiation factor-15 (GDF-15) assay in a Caucasian population and its potential utility in diabetic kidney disease (DKD)

Author(s): Siobhan M. Hamon, Tomás P. Griffin, Md Nahidul Islam, Deirdre Wall, Matthew D. Griffin, Paula M. O’Shea
Published in: Clinical Chemistry and Laboratory Medicine (CCLM), Issue 0/0, 2018, ISSN 1434-6621
DOI: 10.1515/cclm-2018-0534

Effect of Sodium Glucose Co-Transporter-2 Inhibition on the Aldosterone/Renin Ratio in Type 2 Diabetes Mellitus

Author(s): Tomás Griffin, Md Islam, Liam Blake, Marcia Bell, Matthew Griffin, Paula O’Shea
Published in: Hormone and Metabolic Research, Issue 51/02, 2019, Page(s) 91-99, ISSN 0018-5043
DOI: 10.1055/a-0794-7026

Allogeneic Mesenchymal Stromal Cells (MSCs) are of Comparable Efficacy to Syngeneic MSCs for Therapeutic Revascularization in C57BKSdb/db Mice Despite the Induction of Alloantibody

Author(s): A. Liew, C. Baustian, D. Thomas, E. Vaughan, C. Sanz-Nogués, M. Creane, X. Chen, S. Alagesan, P. Owens, J. Horan, P. Dockery, M. D. Griffin, A. Duffy, T. O’Brien
Published in: Cell Transplantation, 2018, Page(s) 096368971878486, ISSN 0963-6897
DOI: 10.1177/0963689718784862

Mesenchymal Stromal Cells for Transplant Tolerance

Author(s): Manuel Alfredo Podestà, Giuseppe Remuzzi, Federica Casiraghi
Published in: Frontiers in Immunology, Issue 10, 2019, ISSN 1664-3224
DOI: 10.3389/fimmu.2019.01287