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CORDIS - Resultados de investigaciones de la UE
CORDIS

Novel Stromal Cell Therapy for Diabetic Kidney Disease

Resultado final

Dissemination materials

Dissemination materials brochure flyer posters newsletters

Website

Website updated throughout the project

Publicaciones

Effects of mesenchymal stromal cells on regulatory T cells: Current understanding and clinical relevance

Autores: Neema Negi, Matthew D. Griffin
Publicado en: STEM CELLS, Edición 38/5, 2020, Página(s) 596-605, ISSN 1066-5099
Editor: AlphaMed Press Inc
DOI: 10.1002/stem.3151

Mesenchymal stromal cell–based therapies for acute kidney injury: progress in the last decade

Autores: Barbara Fazekas, Matthew D. Griffin
Publicado en: Kidney International, Edición 97/6, 2020, Página(s) 1130-1140, ISSN 0085-2538
Editor: Blackwell Publishing Inc.
DOI: 10.1016/j.kint.2019.12.019

The impact of chronic kidney disease on developed countries from a health economics perspective: A systematic scoping review

Autores: Sarah Elshahat, Paul Cockwell, Alexander P. Maxwell, Matthew Griffin, Timothy O’Brien, Ciaran O’Neill
Publicado en: PLOS ONE, Edición 15/3, 2020, Página(s) e0230512, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0230512

Burden of chronic kidney disease and rapid decline in renal function among adults attending a hospital-based diabetes center in Northern Europe

Autores: Tomás P Griffin, Paula M O'Shea, Andrew Smyth, Md Nahidul Islam, Deirdre Wall, John Ferguson, Esther O'Sullivan, Francis M Finucane, Sean F Dinneen, Fidelma P Dunne, David W Lappin, Donal N Reddan, Marcia Bell, Timothy O'Brien, Damian G Griffin, Matthew D Griffin
Publicado en: BMJ Open Diabetes Research & Care, Edición 9/1, 2021, Página(s) e002125, ISSN 2052-4897
Editor: BMJ Open Diabetes Research and Care
DOI: 10.1136/bmjdrc-2021-002125

Chronic kidney disease

Autores: Paola Romagnani, Giuseppe Remuzzi, Richard Glassock, Adeera Levin, Kitty J. Jager, Marcello Tonelli, Ziad Massy, Christoph Wanner, Hans-Joachim Anders
Publicado en: Nature Reviews Disease Primers, Edición 3, 2017, Página(s) 17088, ISSN 2056-676X
Editor: Nature Reviews
DOI: 10.1038/nrdp.2017.88

Anti-Donor Immune Responses Elicited by Allogeneic Mesenchymal Stem Cells and Their Extracellular Vesicles: Are We Still Learning?

Autores: Paul Lohan, Oliver Treacy, Matthew D. Griffin, Thomas Ritter, Aideen E. Ryan
Publicado en: Frontiers in Immunology, Edición 8, 2017, ISSN 1664-3224
Editor: Frontiers in Immunology
DOI: 10.3389/fimmu.2017.01626

Influence of Referral to a Combined Diabetology and Nephrology Clinic on Renal Functional Trends and Metabolic Parameters in Adults With Diabetic Kidney Disease

Autores: William P. Martin, Tomás P. Griffin, David W. Lappin, Damian G. Griffin, John P. Ferguson, Timothy O'Brien, Matthew D. Griffin
Publicado en: Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Edición 1/2, 2017, Página(s) 150-160, ISSN 2542-4548
Editor: Elsevier
DOI: 10.1016/j.mayocpiqo.2017.07.003

Interspecies Incompatibilities Limit the Immunomodulatory Effect of Human Mesenchymal Stromal Cells in the Rat

Autores: Paul Lohan, Oliver Treacy, Maurice Morcos, Ellen Donohoe, Yvonne O'donoghue, Aideen E. Ryan, Stephen J. Elliman, Thomas Ritter, Matthew D. Griffin
Publicado en: STEM CELLS, 2018, ISSN 1066-5099
Editor: AlphaMed Press Inc
DOI: 10.1002/stem.2840

Hyperactivation of nuclear receptor coactivators induces PERK-dependent cell death

Autores: Muhammad Mosaraf Hossain, David Barua, Vahid Arabkari, Nahidul Islam, Ananya Gupta, Sanjeev Gupta
Publicado en: Oncotarget, Edición 9/14, 2018, ISSN 1949-2553
Editor: Impact Journals
DOI: 10.18632/oncotarget.24451

Anti-donor antibody induction following intramuscular injections of allogeneic mesenchymal stromal cells

Autores: Senthilkumar Alagesan, Clara Sanz-Nogués, Xizhe Chen, Michael Creane, Thomas Ritter, Rhodri Ceredig, Timothy O'Brien, Matthew D Griffin
Publicado en: Immunology and Cell Biology, Edición 96/5, 2018, Página(s) 536-548, ISSN 0818-9641
Editor: Blackwell Publishing Inc.
DOI: 10.1111/imcb.12024

Phenotypic and functional heterogeneity of human intermediate monocytes based on HLA-DR expression

Autores: Eanna P Connaughton, Serika Naicker, Shirley A Hanley, Stephanie M Slevin, John K Eykelenboom, Noel F Lowndes, Timothy O'Brien, Rhodri Ceredig, Matthew D Griffin, Michael C Dennedy
Publicado en: Immunology and Cell Biology, 2018, ISSN 0818-9641
Editor: Blackwell Publishing Inc.
DOI: 10.1111/imcb.12032

The Promise of Mesenchymal Stem Cell Therapy for Diabetic Kidney Disease

Autores: Tomás P. Griffin, William Patrick Martin, Nahidul Islam, Timothy O’Brien, Matthew D. Griffin
Publicado en: Current Diabetes Reports, Edición 16/5, 2016, ISSN 1534-4827
Editor: Current Science Inc.
DOI: 10.1007/s11892-016-0734-6

Clinical Translation of Mesenchymal Stromal Cell Therapies in Nephrology

Autores: Norberto Perico, Federica Casiraghi, Giuseppe Remuzzi
Publicado en: Journal of the American Society of Nephrology, Edición 29/2, 2018, Página(s) 362-375, ISSN 1046-6673
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/ASN.2017070781

Mesenchymal Stromal Cells for AKI after Cardiac Surgery

Autores: Norberto Perico, Federica Casiraghi, Giuseppe Remuzzi
Publicado en: Journal of the American Society of Nephrology, 2018, Página(s) ASN.2017111207, ISSN 1046-6673
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/ASN.2017111207

The Immune System in Tissue Environments Regaining Homeostasis after Injury: Is “Inflammation” Always Inflammation?

Autores: Onkar P. Kulkarni, Julia Lichtnekert, Hans-Joachim Anders, Shrikant R. Mulay
Publicado en: Mediators of Inflammation, Edición 2016, 2016, Página(s) 1-9, ISSN 0962-9351
Editor: Hindawi Publishing Corporation
DOI: 10.1155/2016/2856213

Chronic kidney disease, health-related quality of life and their associated economic burden among a nationally representative sample of community dwelling adults in England

Autores: Nga T. Q. Nguyen, Paul Cockwell, Alexander P. Maxwell, Matthew Griffin, Timothy O’Brien, Ciaran O’Neill
Publicado en: PLOS ONE, Edición 13/11, 2018, Página(s) e0207960, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0207960

Defining reference intervals for a serum growth differentiation factor-15 (GDF-15) assay in a Caucasian population and its potential utility in diabetic kidney disease (DKD)

Autores: Siobhan M. Hamon, Tomás P. Griffin, Md Nahidul Islam, Deirdre Wall, Matthew D. Griffin, Paula M. O’Shea
Publicado en: Clinical Chemistry and Laboratory Medicine (CCLM), Edición 0/0, 2018, ISSN 1434-6621
Editor: Walter de Gruyter GmbH & Co. KG
DOI: 10.1515/cclm-2018-0534

Effect of Sodium Glucose Co-Transporter-2 Inhibition on the Aldosterone/Renin Ratio in Type 2 Diabetes Mellitus

Autores: Tomás Griffin, Md Islam, Liam Blake, Marcia Bell, Matthew Griffin, Paula O’Shea
Publicado en: Hormone and Metabolic Research, Edición 51/02, 2019, Página(s) 91-99, ISSN 0018-5043
Editor: Georg Thieme Verlag
DOI: 10.1055/a-0794-7026

Allogeneic Mesenchymal Stromal Cells (MSCs) are of Comparable Efficacy to Syngeneic MSCs for Therapeutic Revascularization in C57BKSdb/db Mice Despite the Induction of Alloantibody

Autores: A. Liew, C. Baustian, D. Thomas, E. Vaughan, C. Sanz-Nogués, M. Creane, X. Chen, S. Alagesan, P. Owens, J. Horan, P. Dockery, M. D. Griffin, A. Duffy, T. O’Brien
Publicado en: Cell Transplantation, 2018, Página(s) 096368971878486, ISSN 0963-6897
Editor: Cognizant Communication Corp.
DOI: 10.1177/0963689718784862

Mesenchymal Stromal Cells for Transplant Tolerance

Autores: Manuel Alfredo Podestà, Giuseppe Remuzzi, Federica Casiraghi
Publicado en: Frontiers in Immunology, Edición 10, 2019, ISSN 1664-3224
Editor: Frontiers in Immunology
DOI: 10.3389/fimmu.2019.01287

Progress toward the clinical application of mesenchymal stromal cells and other disease-modulating regenerative therapies

Autores: LaTonya J. Hickson, Sandra M. Herrmann, Bairbre A. McNicholas, Matthew D. Griffin
Publicado en: Kidney360, 2021, Página(s) 10.34067/KID.0005692020, ISSN 2641-7650
Editor: American Society of Nephrology
DOI: 10.34067/kid.0005692020

Human mesenchymal stromal cells broadly modulate high glucose-induced inflammatory responses of renal proximal tubular cell monolayers

Autores: Md Nahidul Islam, Tomás P. Griffin, Elizabeth Sander, Stephanie Rocks, Junaid Qazi, Joana Cabral, Jasmin McCaul, Tara McMorrow, Matthew D. Griffin
Publicado en: Stem Cell Research & Therapy, Edición 10/1, 2019, Página(s) online, ISSN 1757-6512
Editor: BioMed Central
DOI: 10.1186/s13287-019-1424-5

Plasma dephosphorylated-uncarboxylated Matrix Gla-Protein (dp-ucMGP): reference intervals in Caucasian adults and diabetic kidney disease biomarker potential

Autores: Tomás Patrick Griffin, Md Nahidul Islam, Deirdre Wall, John Ferguson, Damian Gerard Griffin, Matthew Dallas Griffin, Paula M. O’Shea
Publicado en: Scientific Reports, Edición 9/1, 2019, Página(s) online, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-019-54762-2

Editorial: Innovative Biologics and Drugs to Target Renal Inflammation

Autores: Matthew D. Griffin, Sundararaman Swaminathan
Publicado en: Frontiers in Pharmacology, Edición 11, 2020, Página(s) online, ISSN 1663-9812
Editor: Frontiers Media S.A.
DOI: 10.3389/fphar.2020.00038

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