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The aging germ cell – biological pathways, risk factors and mechanisms underlying an increasing medical and socio-economic problem

Deliverables

Public web site

The initial version of the website will contain the collaboration and communication tools and it will describe the vision and of the project as well as the structure and role of the partners. The enhanced version will additionally contain the specific section targeted to the end users.

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Publications

CTCF contributes in a critical way to spermatogenesis and male fertility

Author(s): Abrahan Hernández-Hernández, Ingrid Lilienthal, Nanaho Fukuda, Niels Galjart, Christer Höög
Published in: Scientific Reports, Issue 6/1, 2016, ISSN 2045-2322
DOI: 10.1038/srep28355

SMC1α Substitutes for Many Meiotic Functions of SMC1β but Cannot Protect Telomeres from Damage

Author(s): Uddipta Biswas, Michelle Stevense, Rolf Jessberger
Published in: Current Biology, Issue 28/2, 2018, Page(s) 249-261.e4, ISSN 0960-9822
DOI: 10.1016/j.cub.2017.12.020

APC/C Cdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity

Author(s): Ahmed Rattani, Randy Ballesteros Mejia, Katherine Roberts, Maurici B. Roig, Jonathan Godwin, Michael Hopkins, Manuel Eguren, Luis Sanchez-Pulido, Elwy Okaz, Sugako Ogushi, Magda Wolna, Jean Metson, Alberto M. Pendás, Marcos Malumbres, Béla Novák, Mary Herbert, Kim Nasmyth
Published in: Current Biology, Issue 27/10, 2017, Page(s) 1462-1476.e5, ISSN 0960-9822
DOI: 10.1016/j.cub.2017.04.023

How Meiosis Creates the Single-Copy Genome

Author(s): Mary Herbert, Attila Toth
Published in: Developmental Cell, Issue 40/1, 2017, Page(s) 3-4, ISSN 1534-5807
DOI: 10.1016/j.devcel.2016.12.019

Sexual dimorphism in the width of the mouse synaptonemal complex

Author(s): Ana Agostinho, Anna Kouznetsova, Abrahan Hernández-Hernández, Kristoffer Bernhem, Hans Blom, Hjalmar Brismar, Christer Höög
Published in: Journal of Cell Science, Issue 131/5, 2018, Page(s) jcs212548, ISSN 0021-9533
DOI: 10.1242/jcs.212548

Meiosis and Maternal Aging: Insights from Aneuploid Oocytes and Trisomy Births

Author(s): Mary Herbert, Dimitrios Kalleas, Daniel Cooney, Mahdi Lamb, Lisa Lister
Published in: Cold Spring Harbor Perspectives in Biology, Issue 7/4, 2015, Page(s) a017970, ISSN 1943-0264
DOI: 10.1101/cshperspect.a017970

High density of REC8 constrains sister chromatid axes and prevents illegitimate synaptonemal complex formation

Author(s): Ana Agostinho, Otto Manneberg, Robin van Schendel, Abrahan Hernández‐Hernández, Anna Kouznetsova, Hans Blom, Hjalmar Brismar, Christer Höög
Published in: EMBO reports, Issue 17/6, 2016, Page(s) 901-913, ISSN 1469-221X
DOI: 10.15252/embr.201642030

Post‐metaphase correction of aberrant kinetochore‐microtubule attachments in mammalian eggs

Author(s): Anna Kouznetsova, Tomoya S Kitajima, Hjalmar Brismar, Christer Höög
Published in: EMBO reports, Issue 20/8, 2019, ISSN 1469-221X
DOI: 10.15252/embr.201947905

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

Author(s): Marcos Morgan, Yuka Kabayama, Christian Much, Ivayla Ivanova, Monica Di Giacomo, Tatsiana Auchynnikava, Jack Michael Monahan, Dimitrios Michael Vitsios, Lina Vasiliauskaitė, Stefano Comazzetto, Juri Rappsilber, Robin Campbell Allshire, Bo Torben Porse, Anton James Enright, Dónal O’Carroll
Published in: Cell Research, Issue 29/3, 2019, Page(s) 221-232, ISSN 1001-0602
DOI: 10.1038/s41422-018-0128-1

Mutations in the stromal antigen 3 (STAG3) gene cause male infertility due to meiotic arrest

Author(s): N van der Bijl, A Röpke, U Biswas, M Wöste, R Jessberger, S Kliesch, C Friedrich, F Tüttelmann
Published in: Human Reproduction, 2019, ISSN 0268-1161
DOI: 10.1093/humrep/dez204

GermAge, The aging germ cell ? biological pathways, risk factors and mechanisms underlying anincreasing medical and socio-economic problem, HORIZON2020

Author(s): Rolf Jessberger
Published in: Impact, Issue 2017/10, 2017, Page(s) 15-17, ISSN 2398-7073
DOI: 10.21820/23987073.2017.10.15