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The aging germ cell – biological pathways, risk factors and mechanisms underlying an increasing medical and socio-economic problem

Rezultaty

Public web site

The initial version of the website will contain the collaboration and communication tools and it will describe the vision and of the project as well as the structure and role of the partners. The enhanced version will additionally contain the specific section targeted to the end users.

Publikacje

Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes

Autorzy: Shuhei Yoshida, Sui Nishiyama, Lisa Lister, Shu Hashimoto, Tappei Mishina, Aurélien Courtois, Hirohisa Kyogoku, Takaya Abe, Aki Shiraishi, Meenakshi Choudhary, Yoshiharu Nakaoka, Mary Herbert, Tomoya S. Kitajima
Opublikowane w: Nature Communications, 11/1, 2020, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-020-16488-y

Oocyte aneuploidy—more tools to tackle an old problem

Autorzy: Chris Lodge, Mary Herbert
Opublikowane w: Proceedings of the National Academy of Sciences, 117/22, 2020, Page(s) 11850-11852, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2005739117

SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation

Autorzy: Ansgar Zoch, Tania Auchynnikava, Rebecca V. Berrens, Yuka Kabayama, Theresa Schöpp, Madeleine Heep, Lina Vasiliauskaitė, Yuvia A. Pérez-Rico, Atlanta G. Cook, Alena Shkumatava, Juri Rappsilber, Robin C. Allshire, Dónal O’Carroll
Opublikowane w: Nature, 584/7822, 2020, Page(s) 635-639, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-020-2557-5

Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2

Autorzy: François McNicoll, Anne Kühnel, Uddipta Biswas, Kai Hempel, Gabriela Whelan, Gregor Eichele, Rolf Jessberger
Opublikowane w: Life Science Alliance, 3/3, 2020, Page(s) e201900564, ISSN 2575-1077
Wydawca: Life Science Alliance
DOI: 10.26508/lsa.201900564

CTCF contributes in a critical way to spermatogenesis and male fertility

Autorzy: Abrahan Hernández-Hernández, Ingrid Lilienthal, Nanaho Fukuda, Niels Galjart, Christer Höög
Opublikowane w: Scientific Reports, 6/1, 2016, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/srep28355

SMC1α Substitutes for Many Meiotic Functions of SMC1β but Cannot Protect Telomeres from Damage

Autorzy: Uddipta Biswas, Michelle Stevense, Rolf Jessberger
Opublikowane w: Current Biology, 28/2, 2018, Page(s) 249-261.e4, ISSN 0960-9822
Wydawca: Cell Press
DOI: 10.1016/j.cub.2017.12.020

APC/C Cdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity

Autorzy: Ahmed Rattani, Randy Ballesteros Mejia, Katherine Roberts, Maurici B. Roig, Jonathan Godwin, Michael Hopkins, Manuel Eguren, Luis Sanchez-Pulido, Elwy Okaz, Sugako Ogushi, Magda Wolna, Jean Metson, Alberto M. Pendás, Marcos Malumbres, Béla Novák, Mary Herbert, Kim Nasmyth
Opublikowane w: Current Biology, 27/10, 2017, Page(s) 1462-1476.e5, ISSN 0960-9822
Wydawca: Cell Press
DOI: 10.1016/j.cub.2017.04.023

How Meiosis Creates the Single-Copy Genome

Autorzy: Mary Herbert, Attila Toth
Opublikowane w: Developmental Cell, 40/1, 2017, Page(s) 3-4, ISSN 1534-5807
Wydawca: Cell Press
DOI: 10.1016/j.devcel.2016.12.019

Sexual dimorphism in the width of the mouse synaptonemal complex

Autorzy: Ana Agostinho, Anna Kouznetsova, Abrahan Hernández-Hernández, Kristoffer Bernhem, Hans Blom, Hjalmar Brismar, Christer Höög
Opublikowane w: Journal of Cell Science, 131/5, 2018, Page(s) jcs212548, ISSN 0021-9533
Wydawca: The Company of Biologists Ltd.
DOI: 10.1242/jcs.212548

Meiosis and Maternal Aging: Insights from Aneuploid Oocytes and Trisomy Births

Autorzy: Mary Herbert, Dimitrios Kalleas, Daniel Cooney, Mahdi Lamb, Lisa Lister
Opublikowane w: Cold Spring Harbor Perspectives in Biology, 7/4, 2015, Page(s) a017970, ISSN 1943-0264
Wydawca: Cold Spring Harbor Laboratory Press
DOI: 10.1101/cshperspect.a017970

High density of REC8 constrains sister chromatid axes and prevents illegitimate synaptonemal complex formation

Autorzy: Ana Agostinho, Otto Manneberg, Robin van Schendel, Abrahan Hernández‐Hernández, Anna Kouznetsova, Hans Blom, Hjalmar Brismar, Christer Höög
Opublikowane w: EMBO reports, 17/6, 2016, Page(s) 901-913, ISSN 1469-221X
Wydawca: Nature Publishing Group
DOI: 10.15252/embr.201642030

Post‐metaphase correction of aberrant kinetochore‐microtubule attachments in mammalian eggs

Autorzy: Anna Kouznetsova, Tomoya S Kitajima, Hjalmar Brismar, Christer Höög
Opublikowane w: EMBO reports, 20/8, 2019, ISSN 1469-221X
Wydawca: Nature Publishing Group
DOI: 10.15252/embr.201947905

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

Autorzy: Marcos Morgan, Yuka Kabayama, Christian Much, Ivayla Ivanova, Monica Di Giacomo, Tatsiana Auchynnikava, Jack Michael Monahan, Dimitrios Michael Vitsios, Lina Vasiliauskaitė, Stefano Comazzetto, Juri Rappsilber, Robin Campbell Allshire, Bo Torben Porse, Anton James Enright, Dónal O’Carroll
Opublikowane w: Cell Research, 29/3, 2019, Page(s) 221-232, ISSN 1001-0602
Wydawca: Kexue Chubaneshe/Science Press
DOI: 10.1038/s41422-018-0128-1

Mutations in the stromal antigen 3 (STAG3) gene cause male infertility due to meiotic arrest

Autorzy: N van der Bijl, A Röpke, U Biswas, M Wöste, R Jessberger, S Kliesch, C Friedrich, F Tüttelmann
Opublikowane w: Human Reproduction, 2019, ISSN 0268-1161
Wydawca: Oxford University Press
DOI: 10.1093/humrep/dez204

Tex19.1 inhibits the N-end rule pathway and maintains acetylated SMC3 cohesin and sister chromatid cohesion in oocytes

Autorzy: Judith Reichmann, Karen Dobie, Lisa M. Lister, James H. Crichton, Diana Best, Marie MacLennan, David Read, Eleanor S. Raymond, Chao-Chun Hung, Shelagh Boyle, Katsuhiko Shirahige, Howard J. Cooke, Mary Herbert, Ian R. Adams
Opublikowane w: Journal of Cell Biology, 219/5, 2020, ISSN 0021-9525
Wydawca: Rockefeller University Press
DOI: 10.1083/jcb.201702123

TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing

Autorzy: Theresa Schöpp, Ansgar Zoch, Rebecca V. Berrens, Tania Auchynnikava, Yuka Kabayama, Lina Vasiliauskaitė, Juri Rappsilber, Robin C. Allshire, Dónal O’Carroll
Opublikowane w: Nature Communications, 11/1, 2020, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-020-17372-5

GermAge, The aging germ cell ? biological pathways, risk factors and mechanisms underlying anincreasing medical and socio-economic problem, HORIZON2020

Autorzy: Rolf Jessberger
Opublikowane w: Impact, 2017/10, 2017, Page(s) 15-17, ISSN 2398-7073
Wydawca: Science ImpactLtd.
DOI: 10.21820/23987073.2017.10.15

Zbiory danych