Skip to main content

A Clinical Decision Support system based on Quantitative multimodal brain MRI for personalized treatment in neurological and psychiatric disorders

Deliverables

Marketing instruments established

project video established; project brochure, information letters and printed communication; website updated

Project Communication Initilization

Project webpage and mailing list established; Exploitation Plan finalized; Project description and updated information appears on project webpage

Searching for OpenAIRE data...

Publications

Aberrant working memory processing in major depression: evidence from multivoxel pattern classification

Author(s): Matti Gärtner, M. Elisabetta Ghisu, Milan Scheidegger, Luisa Bönke, Yan Fan, Anna Stippl, Ana-Lucia Herrera-Melendez, Sophie Metz, Emilia Winnebeck, Maria Fissler, Anke Henning, Malek Bajbouj, Karsten Borgwardt, Thorsten Barnhofer, Simone Grimm
Published in: Neuropsychopharmacology, Issue 43/9, 2018, Page(s) 1972-1979, ISSN 0893-133X
DOI: 10.1038/s41386-018-0081-1

Deep gray matter volume loss drives disability worsening in multiple sclerosis


Published in: ISSN 0364-5134
DOI: 10.1002/ana.25145

graphkernels: R and Python packages for graph comparison

Author(s): Mahito Sugiyama, M Elisabetta Ghisu, Felipe Llinares-López, Karsten Borgwardt
Published in: Bioinformatics, Issue 34/3, 2017, Page(s) 530-532, ISSN 1367-4803
DOI: 10.1093/bioinformatics/btx602

Neurite dispersion: a new marker of multiple sclerosis spinal cord pathology?

Author(s): Francesco Grussu, Torben Schneider, Carmen Tur, Richard L. Yates, Mohamed Tachrount, Andrada Ianuş, Marios C. Yiannakas, Jia Newcombe, Hui Zhang, Daniel C. Alexander, Gabriele C. DeLuca, Claudia A. M. Gandini Wheeler-Kingshott
Published in: Annals of Clinical and Translational Neurology, Issue 4/9, 2017, Page(s) 663-679, ISSN 2328-9503
DOI: 10.1002/acn3.445

LISA improves statistical analysis for fMRI

Author(s): Gabriele Lohmann, Johannes Stelzer, Eric Lacosse, Vinod J. Kumar, Karsten Mueller, Esther Kuehn, Wolfgang Grodd, Klaus Scheffler
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
DOI: 10.1038/s41467-018-06304-z

MultiNet PyGRAPPA: Multiple neural networks for reconstructing variable density GRAPPA (a 1H FID MRSI study)

Author(s): Sahar Nassirpour, Paul Chang, Anke Henning
Published in: NeuroImage, Issue 183, 2018, Page(s) 336-345, ISSN 1053-8119
DOI: 10.1016/j.neuroimage.2018.08.032

Task-Related Edge Density (TED)—A New Method for Revealing Dynamic Network Formation in fMRI Data of the Human Brain

Author(s): Gabriele Lohmann, Johannes Stelzer, Verena Zuber, Tilo Buschmann, Daniel Margulies, Andreas Bartels, Klaus Scheffler
Published in: PLOS ONE, Issue 11/6, 2016, Page(s) e0158185, ISSN 1932-6203
DOI: 10.1371/journal.pone.0158185

Measuring the labeling efficiency of pseudocontinuous arterial spin labeling


Published in: ISSN 0740-3194
DOI: 10.1002/mrm.26266

Multi-compartment microscopic diffusion imaging

Author(s): Enrico Kaden, Nathaniel D. Kelm, Robert P. Carson, Mark D. Does, Daniel C. Alexander
Published in: NeuroImage, Issue 139, 2016, Page(s) 346-359, ISSN 1053-8119
DOI: 10.1016/j.neuroimage.2016.06.002

Brainglance: Visualizing Group Level MRI Data at One Glance

Author(s): Johannes Stelzer, Eric Lacosse, Jonas Bause, Klaus Scheffler, Gabriele Lohmann
Published in: Frontiers in Neuroscience, Issue 13, 2019, ISSN 1662-453X
DOI: 10.3389/fnins.2019.00972

Multi-parametric quantitative in vivo spinal cord MRI with unified signal readout and image denoising

Author(s): Francesco Grussu, Marco Battiston, Jelle Veraart, Torben Schneider, Julien Cohen-Adad, Timothy M. Shepherd, Daniel C. Alexander, Els Fieremans, Dmitry S. Novikov, Claudia A.M. Gandini Wheeler-Kingshott
Published in: NeuroImage, Issue 217, 2020, Page(s) 116884, ISSN 1053-8119
DOI: 10.1016/j.neuroimage.2020.116884

Functional connectivity between prefrontal cortex and subgenual cingulate predicts antidepressant effects of ketamine

Author(s): Matti Gärtner, Sabine Aust, Malek Bajbouj, Yan Fan, Katja Wingenfeld, Christian Otte, Isabella Heuser-Collier, Heinz Böker, Josef Hättenschwiler, Erich Seifritz, Simone Grimm, Milan Scheidegger
Published in: European Neuropsychopharmacology, Issue 29/4, 2019, Page(s) 501-508, ISSN 0924-977X
DOI: 10.1016/j.euroneuro.2019.02.008

Microscopic susceptibility anisotropy imaging


Published in: ISSN 0740-3194
DOI: 10.1002/mrm.28303

Fast and reproducible in vivo T 1 mapping of the human cervical spinal cord


Published in: ISSN 0740-3194
DOI: 10.1002/mrm.26852

Reduced neurite density in the brain and cervical spinal cord in relapsing–remitting multiple sclerosis: A NODDI study

Author(s): Collorone, Sara; Cawley, Niamh; Grussu, Francesco; Prados, Ferran; Tona, Francesca; Calvi, Alberto; Kanber, Baris; Schneider, Torben; Kipp, Lucas; Zhang, Hui; Alexander, Daniel C; Thompson, Alan J; Toosy, Ahmed; Wheeler-Kingshott, Claudia AM Gandini; Ciccarelli, Olga
Published in: Multiple Sclerosis Journal, Issue 19, 2019, Page(s) 135245851984510, ISSN 1352-4585
DOI: 10.1177/1352458519885107

A multi-shell multi-tissue diffusion study of brain connectivity in early multiple sclerosis

Author(s): Carmen Tur, Francesco Grussu, Ferran Prados, Thalis Charalambous, Sara Collorone, Baris Kanber, Niamh Cawley, Daniel R Altmann, Sébastien Ourselin, Frederik Barkhof, Jonathan D Clayden, Ahmed T Toosy, Claudia AM Gandini Wheeler-Kingshott, Olga Ciccarelli
Published in: Multiple Sclerosis Journal, 2019, Page(s) 135245851984510, ISSN 1352-4585
DOI: 10.1177/1352458519845105

Generalised boundary shift integral for longitudinal assessment of spinal cord atrophy

Author(s): Prados, Ferran; Moccia, Marcello; Johnson, Aubrey; Yiannakas, Marios; Grussu, Francesco; Cardoso, Manuel Jorge; Ciccarelli, Olga; Ourselin, Sebastien; Barkhof, Frederik; Wheeler-Kingshott, Claudia
Published in: NeuroImage, Issue 209, 2020, Page(s) 116489, ISSN 1053-8119
DOI: 10.1016/j.neuroimage.2019.116489

Cross-scanner and cross-protocol diffusion MRI data harmonisation: A benchmark database and evaluation of algorithms

Author(s): Tax, Chantal M. W.; Grussu, Francesco; Kaden, Enrico; Ning, Lipeng; Rudrapatna, Umesh; Evans, C. John; St-Jean, Samuel; Leemans, Alexander; Koppers, Simon; Merhof, Dorit; Ghosh, Aurobrata; Tanno, Ryutaro; Alexander, Daniel C.; Zappala, Stefano; Charron, Cyril; Kusmia, Slawomir; Linden, David E. J.; Jones, Derek K.; Veraart, Jelle
Published in: NeuroImage, Issue 195, 2019, Page(s) 285, ISSN 1053-8119
DOI: 10.1016/j.neuroimage.2019.01.077

Probing axons using multi‐compartmental diffusion in multiple sclerosis

Author(s): Francesca Bagnato, Giulia Franco, Hua Li, Enrico Kaden, Fei Ye, Run Fan, Amalie Chen, Daniel C. Alexander, Seth A. Smith, Richard Dortch, Junzhong Xu
Published in: Annals of Clinical and Translational Neurology, Issue 6/9, 2019, Page(s) 1595-1605, ISSN 2328-9503
DOI: 10.1002/acn3.50836

White matter microstructural abnormalities in children with severe congenital hypothyroidism

Author(s): Hannah E. Cooper, Enrico Kaden, Lorna F. Halliday, Doris-Eva Bamiou, Kshitij Mankad, Catherine Peters, Christopher A. Clark
Published in: NeuroImage: Clinical, Issue 24, 2019, Page(s) 101980, ISSN 2213-1582
DOI: 10.1016/j.nicl.2019.101980

Structural cortical network reorganization associated with early conversion to multiple sclerosis

Author(s): C. Tur, A. Eshaghi, D. R. Altmann, T. M. Jenkins, F. Prados, F. Grussu, T. Charalambous, A. Schmidt, S. Ourselin, J. D. Clayden, C. A. M. G. Wheeler-Kingshott, A. J. Thompson, O. Ciccarelli, A. T. Toosy
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
DOI: 10.1038/s41598-018-29017-1

Spinal cord grey matter segmentation challenge

Author(s): Ferran Prados, John Ashburner, Claudia Blaiotta, Tom Brosch, Julio Carballido-Gamio, Manuel Jorge Cardoso, Benjamin N. Conrad, Esha Datta, Gergely Dávid, Benjamin De Leener, Sara M. Dupont, Patrick Freund, Claudia A.M. Gandini Wheeler-Kingshott, Francesco Grussu, Roland Henry, Bennett A. Landman, Emil Ljungberg, Bailey Lyttle, Sebastien Ourselin, Nico Papinutto, Salvatore Saporito, Regina Schlaeg
Published in: NeuroImage, Issue 152, 2017, Page(s) 312-329, ISSN 1053-8119
DOI: 10.1016/j.neuroimage.2017.03.010

A framework for optimal whole-sample histological quantification of neurite orientation dispersion in the human spinal cord

Author(s): Francesco Grussu, Torben Schneider, Richard L. Yates, Hui Zhang, Claudia A.M. Gandini Wheeler-Kingshott, Gabriele C. DeLuca, Daniel C. Alexander
Published in: Journal of Neuroscience Methods, Issue 273, 2016, Page(s) 20-32, ISSN 0165-0270
DOI: 10.1016/j.jneumeth.2016.08.002

Inflated False Negative Rates Undermine Reproducibility In Task-Based fMRI

Author(s): Gabriele Lohmann, Johannes Stelzer, Karsten Mueller, Eric Lacosse, Tilo Buschmann, Vinod J. Kumar, Wolfgang Grodd, Klaus Scheffler
Published in: BioRxiv, 2017, ISSN 1097-0193
DOI: 10.1101/122788

Eigenvector centrality mapping for ultrahigh resolution fMRI data.

Author(s): Gabriele Lohmann, Alexander Loktyushin, Johannes Stelzer, Klaus Scheffler.
Published in: BioRxiv, 2019, ISSN 1097-0193
DOI: 10.1101/494732

Improved Spatial encoding of vessel-selective pCASL: improving efficiency, minimising mislabelling, and shortening scan-time for artery specific MRA.

Author(s): Suzuki, Y., van Osch, M. J.P. and Okell, TW.
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2017, 2017, Page(s) 3617

Qualitative Comparison between In Vivo J-Resolved Semi-LASER at 3 T and 9.4 T.

Author(s): Venkateshwaran Murali Manohar Saipavitra, Giapitzakis Ioannis Angelos, Borbáth Tamás, Gärtner Matti, Henning Anke
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2017, 2017, Page(s) 3015

Fitting comparison for 9.4T 1D semi-LASER and 2D-J-resolved semi-LASER data.

Author(s): Borbáth Tamás, Giapitzakis Ioannis Angelos, Venkateshwaran Murali Manohar Saipavitra, Henning Anke
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2017, 2017, Page(s) 2995

Silving the dark-side of multiband-ASL: A framework to correct for increased motion artefacts in MB-ASL due to sharp transitions in the level of background suppression.

Author(s): Suzuki, Y., Okell, TW., Teeuwisse, WM., Schmid, S., van der Plas, M., Chappell, MA., and van Osch, M. J.P.
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2017, 2017, Page(s) 3616

Reproducibility of SMT-Based Microscopic Diffusion Anisotropy Imaging on a Clinical MRI System

Author(s): Foley Cara, Kaden Enrico, Seunarine Kiran, Hall Matt, Carmichael David, Clayden Jonathan, Clark Chris
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2017, 2017, Page(s) 3471

Origin of the Time Dependence of the Diffusion-Weighted Signal in Spinal Cord White Matter.

Author(s): Grussu Francesco, Ianus Andrada, Tur Carmen, Prados Ferran, Schneider Torben, Ourselin Sébastien, Drobnjak Ivana, Zhang Hui, Alexander Daniel, Gandini Wheeler-Kingshott Claudia
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2017, 2017, Page(s) 0843

A Unified Signal Readout for Reproducible Multimodal Characterisation of Brain Microstructure

Author(s): Grussu Francesco, Battiston Marco, Prados Ferran, Schneider Torben, Kaden Enrico, Ourselin Sébastien, Samson Rebecca, Alexander Daniel, Gandini Wheeler-Kingshott Claudia
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2017, 2017, Page(s) 3399

Towards a Fitting Model of Macromolecular Spectra: Amino Acids.

Author(s): Tamas Borbath, Saipavitra Murali Manohar, Anke Henning.
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2019, 2019, Page(s) 27/1068

Longitudinal Relaxation Times of Metabolites in vivo at 9.4 T.

Author(s): Andrew Wright, Saipavitra Murali-Manohar, Tamas Borbath.
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2019, 2019, Page(s) 27/514

T2 Relaxation Times of Macromolecules in Human Brain Spectra at 9.4 T.

Author(s): Tamas Borbath, Saipavitra Murali Manohar, Andrew Wright, Anke Henning.
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2019, 2019

Characterization of Downfield Resonances and their T2 Relaxation times in Human Brain at 9.4 T.

Author(s): Saipavitra Murali-Manohar, Tamas Borbath, Andrew Wright, Anke Henning.
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2019, 2019

Longitudinal Relaxation times of Macromolecular Resonances at 9.4 T in Human Brain.

Author(s): Saipavitra Murali-Manohar, Andrew Wright, Tamas Borbath, Anke Henning.
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2019, 2019

Relaxation corrected and Sequence-dependent Macromolecule Baseline Model.

Author(s): Andrew Wright, Saipavitra Murali Manohar, Anke Henning.
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2019, 2019

Myelin-sensitive indices in multiple sclerosis: the unseen qualities of qualitative clinical MRI.

Author(s): Antonio Ricciardi, Francesco Grussu, Marco Battiston, Ferran Prados, Baris Kanber, Rebecca S Samson, Daniel C Alexander, Declan T Chard, Claudia A M Gandini Wheeler-Kingshott.
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2019, 2019

In-vivo neural soma imaging using b-tensor encoding and deep learning.

Author(s): Noemi G. Gyori, Christopher A. Clark, Iulius Dragonu, Daniel C. Alexander, Enrico Kaden.
Published in: Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM)., Issue 2019, 2019

Bipartite connectivity mapping (BCM).

Author(s): Gabriele Lohmann, Johannes Stelzer, Klaus Scheffler.
Published in: Biennial Conference on Resting-State and Brain Connectivity., Issue 2018, 2018

T1 Relaxation Times of Macromolecular Resonances for Grey and White Matter Voxels in Human Brain at 9.4 T.

Author(s): Saipavitra Murali Manohar, Andrew Wright, Anke Henning.
Published in: Annual Scientific Meeting of the ESMRMB, Issue 2019, 2019

Estimation of T2 Relaxation Times and Absolute Quantification of Metabolites in the Human Brain at 9.4 T.

Author(s): Saipavitra Murali-Manohar, Tamas Borbath, Anke Henning.
Published in: Annual Scientific Meeting of the ESMRMB, Issue 2019, 2019

A simplified approach to quantification of multiple contrasts from time-encoded ASL.

Author(s): Lena Vaclavu , C Falcon, J Domingo, P. Montesinos Suárez de la Vega, Matthias van Osch.
Published in: Annual Scientific Meeting of the ESMRMB, Issue 2019, 2019

Post-Acquisition Correction of Macromolecules using a Relaxation- and Sequence-dependent Simulation Model.

Author(s): Andrew Wright, Saipavitra Murali Manohar, Anke Henning.
Published in: Annual Scientific Meeting of the ESMRMB, Issue 2019, 2019