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EU-TOPIA: TOWARDS IMPROVED SCREENING FOR BREAST, CERVICAL AND COLORECTAL CANCER IN ALL OF EUROPE

Objective

Breast, colorectal and cervical cancer cause 250,000 deaths each year, representing 20% of EU-cancer mortality. Although important progress has been made in both detection and treatment, there is persisting inequity in progress to reduce its burden. Screening programmes vary substantially between countries and in most long-term effectiveness of screening has not yet been assessed. The objective of EU-TOPIA is to systematically evaluate and quantify the harms and benefits of the running programmes for breast, cervical, and colorectal cancer in all European countries, and identify ways to improve health outcomes and equity for citizens. We will first identify significant inequities in screening outcomes by assessing the key set of quality indicators for benefits and harms in each country. Using these indicators, outcomes and cost-effectiveness of existing cancer screening programmes in 2015 will be estimated. For this, state-of-the-art models of the natural history of the cancers will be constructed, using country-specific data with and from country-specific experts. Barriers hindering implementation of optimal screening programs will be assessed, leading to road maps for improved screening. These road maps contain feasible changes, e.g., to extend or reduce the program, to change the screen test used or change key quality indicators, to perform activities that reduce screen-related harm or incorporate new developments in screening, and provide policymakers with evidence for increased, decreased or optimized use of screening. Capacity for self-evaluation of screening will be built using three web-based tools (monitoring, model-quantification and barrier assessment) explained and trained in workshops with country representatives, also from the Associated Countries. The project will lead to reduced inequity, reduced number of cancer deaths and over-diagnosed cases, and increase in life years gained and better cost-effectiveness by 2025. That is why we call it EU-TOPIA.

Field of science

  • /medical and health sciences/clinical medicine/cancer/cervical cancer
  • /medical and health sciences/clinical medicine/cancer/colorectal cancer
  • /social sciences/sociology/demography/mortality
  • /medical and health sciences/clinical medicine/cancer/breast cancer

Call for proposal

H2020-PHC-2014-two-stage
See other projects for this call

Funding Scheme

RIA - Research and Innovation action
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Coordinator

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 613 687,50

Participants (6)

LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER
United Kingdom
EU contribution
€ 298 405
Address
Keppel Street
WC1E 7HT London
Activity type
Higher or Secondary Education Establishments
SUOMEN SYOPAYHDISTYS -CANCERFORENINGEN I FINLAND RY - CANCER SOCIETY OF FINLAND CSF
Finland
EU contribution
€ 245 000
Address
Unioninkatu 22
00130 Helsinki
Activity type
Research Organisations
AZIENDA OSPEDALIERA CITTA DELLA SALUTE E DELLA SCIENZA DI TORINO
Italy
EU contribution
€ 309 025
Address
Corso Bramante 88 90
10126 Torino
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
ONKOLOSKI INSTITUT LJUBLJANA
Slovenia
EU contribution
€ 172 440,50
Address
Zaloska Cesta 2
1000 Ljubljana
Activity type
Research Organisations
TERVISE ARENGU INSTITUUT
Estonia
EU contribution
€ 103 875
Address
Hiiu 42
11619 Tallinn
Activity type
Research Organisations
SYREON KUTATO INTEZET KORLATOLT FELELOSSEGU TARSASAG
Hungary
EU contribution
€ 253 250
Address
Mexikoi Ut 65/A
1142 Budapest
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)