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Laser Multiplexed Biosensor

Objective

Differential cancer diagnosis takes place daily in clinical settings for a better monitoring of patient responses to existing treatments. However outcome of this diagnosis is today still poor. Moreover, current technology to measure biomarker levels is expensive and sophisticated.
Most cancer biomarker analysis use blood or biological tissues as the main source of material. These biopsies must be analyzed in specialized laboratories incurring in some limitations: high cost; specialized personnel and equipment; large amounts of biological material; long outcome delivery time; time consuming processes.
Therefore it exist a real need and urgency to have new diagnostic devices that provide diagnosis, prognosis, and monitoring data faster and with exquisite ultra-sensitivity on time to take the appropriate decisions to improve personalized diagnosis and therapy.
The aim of GLAM project is to provide an innovative device to fulfill these requirements using soluble biomarkers for personalized diagnosis and therapy monitoring.
Specifically we will design and develop a new diagnostic tool to detect biomarkers from biofluids obtained in a non-invasive manner, specifically focusing to urine and to genitourinary cancers, to help oncologist to take better treatment decisions, approaching personalized medicine.
GLAM will develop an integrated device based on novel label-free photonic biosensors with ultra-sensitivity, simplicity of use, portability, multiplexing and low cost. GLAM capitalizes on the unprecedented sensitivity achieved using laser microring resonators to detect key biomarkers in tumor development and treatment. Point of Care of the device will be carried out by preclinical and clinical sample analysis of genitourinary cancer patients to warrant personalized medicine.
Importantly the GLAM unique technology will make the device also usable with other biofluids and might also be used to help physicians with other biomarker driven.

Field of science

  • /medical and health sciences/clinical medicine/oncology/cancer
  • /medical and health sciences/clinical medicine/oncology
  • /natural sciences/physical sciences/optics/laser physics
  • /engineering and technology/environmental biotechnology/biosensing

Call for proposal

H2020-PHC-2014-two-stage
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

ACONDICIONAMIENTO TARRASENSE ASSOCIACION
Address
Carrer De La Innovacio 2
08225 Terrassa
Spain
Activity type
Research Organisations
EU contribution
€ 692 632,50

Participants (9)

FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
Spain
EU contribution
€ 491 125,50
Address
Carrer Baldiri Reixac Planta 2A 10-12
08028 Barcelona
Activity type
Research Organisations
UNIVERSITEIT TWENTE
Netherlands
EU contribution
€ 817 885
Address
Drienerlolaan 5
7522 NB Enschede
Activity type
Higher or Secondary Education Establishments
WINZSOFT (ISRAEL) LTD
Israel
EU contribution
€ 323 625
Address
Beit Hillel 3
67017 Tel Aviv-jaffo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITE LIBRE DE BRUXELLES
Belgium
EU contribution
€ 374 412,50
Address
Avenue Franklin Roosevelt 50
1050 Bruxelles
Activity type
Higher or Secondary Education Establishments
FUNDACIO INSTITUT DE CIENCIES FOTONIQUES
Spain
EU contribution
€ 574 275
Address
Avinguda Carl Friedrich Gauss 3
08860 Castelldefels
Activity type
Research Organisations
STICHTING KATHOLIEKE UNIVERSITEIT
Netherlands
EU contribution
€ 283 316
Address
Geert Grooteplein Noord 9
6525 EZ Nijmegen
Activity type
Higher or Secondary Education Establishments
NOVELIC DOO BEOGRAD-NOVI BEOGRAD
Serbia
EU contribution
€ 467 700
Address
Omladinskih Brigada 86 P
11070 Beograd
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ALTER TECHNOLOGY TUV NORD UK LIMITED
United Kingdom
EU contribution
€ 400 812,50
Address
Bain Square 5
EH54 7DQ Livingston
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
OBELIS SA
Belgium
EU contribution
€ 409 800
Address
Boulevard General Wahis 53
1030 Bruxelles
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)